PMID- 24791267 OWN - NLM STAT- MEDLINE DCOM- 20150904 LR - 20140505 IS - 2327-2228 (Electronic) IS - 0363-7913 (Linking) VI - 97 IP - 5 DP - 2014 May 1 TI - Solitary pulmonary nodule: pleuropulmonary synovial sarcoma. PG - 40-3 AB - Pleuropulmonary synovial sarcoma (PPSS) is an extremely rare primary malignancy of the lung. We present a case of a middle-aged female with PPSS that was initially discovered as an incidental indeterminate nodule on chest radiograph. Following evaluation with computed tomography (CT), the patient went on to positron-emission tomography (PET)/CT for work-up of the solitary pulmonary nodule, which demonstrated mild FDG-avidity and no other evidence of FDG-avid disease. The patient then underwent thoracotomy and right upper lobectomy for definitive treatment. Only after evaluation of the gross pathology, histology, immunohistochemistry and cytogenetics was the diagnosis of synovial sarcoma made. Importantly, the preceding PET/CT, in addition to physical exam of the upper and lower extremities, helped exclude the more common extra-thoracic soft-tissue variety of synovial sarcoma, which frequently metastasizes to lung, carrying a worse prognosis. Discussion of synovial sarcoma and PPSS follows. FAU - Ward, Robert C AU - Ward RC AD - Resident in the Department of Diagnostic Imaging, Warren Alpert Medical School of Brown University, and Rhode Island Hospital, Providence, RI. FAU - Birnbaum, Ariel E AU - Birnbaum AE AD - Assistant Professor of Medicine, Warren Alpert Medical School of Brown University, and Rhode Island Hospital, Providence, RI. FAU - Aswad, Bassam I AU - Aswad BI AD - Associate Professor of Pathology, Warren Alpert Medical School of Brown University, and Rhode Island Hospital, Providence, RI. FAU - Healey, Terrance T AU - Healey TT AD - Assistant Professor of Diagnostic Imaging, Warren Alpert Medical School of Brown University, and Rhode Island Hospital, Providence, RI. LA - eng PT - Case Reports PT - Journal Article DEP - 20140501 PL - United States TA - R I Med J (2013) JT - Rhode Island medical journal (2013) JID - 101605827 SB - IM MH - Adult MH - Female MH - Humans MH - Incidental Findings MH - *Lung Neoplasms/diagnosis/surgery MH - *Pleural Neoplasms/diagnosis/surgery MH - *Sarcoma, Synovial/diagnosis/surgery MH - *Solitary Pulmonary Nodule/diagnosis/surgery OTO - NOTNLM OT - Lung cancer OT - Sarcoma OT - Solitary pulmonary nodule OT - Synovial sarcoma EDAT- 2014/05/03 06:00 MHDA- 2015/09/05 06:00 CRDT- 2014/05/03 06:00 PHST- 2014/05/03 06:00 [entrez] PHST- 2014/05/03 06:00 [pubmed] PHST- 2015/09/05 06:00 [medline] PST - epublish SO - R I Med J (2013). 2014 May 1;97(5):40-3.