PMID- 24795090
OWN - NLM
STAT- MEDLINE
DCOM- 20150402
LR  - 20220321
IS  - 1460-2350 (Electronic)
IS  - 0268-1161 (Linking)
VI  - 29
IP  - 7
DP  - 2014 Jul
TI  - International Committee for Monitoring Assisted Reproductive Technologies world 
      report: Assisted Reproductive Technology 2006.
PG  - 1536-51
AB  - STUDY QUESTION: What are the access, effectiveness and safety of assisted 
      reproductive technology (ART) worldwide in 2006? SUMMARY ANSWER: ART access, 
      effectiveness and safety vary markedly among countries. Overall, there was an 
      increase in the use of ICSI, single embryo transfer (SET) and frozen embryo 
      transfer (FET). There was a decline in the multiple delivery rate (DR) and 
      preterm birth rate. WHAT IS KNOWN ALREADY: ART is widely practiced worldwide and 
      there is a need for its continuous monitoring to improve the comprehensiveness 
      and quality of ART data and services. STUDY DESIGN, SIZE, DURATION: This is a 
      retrospective, cross-sectional survey of ART cycles undertaken worldwide in 2006. 
      PARTICIPANTS, SETTING, METHODS: A total of 2352 clinics in 56 countries provided 
      data. Data were analyzed at a country and regional level. The forms for data 
      collection were developed by the International Committee Monitoring Assisted 
      Reproductive Technologies (ICMART) and sent to each country or regional ART 
      register. MAIN RESULTS AND THE ROLE OF CHANCE: A total of >1,050,300 initiated 
      cycles resulted in an estimated >256,668 babies. The overall pregnancy rates 
      (PRs) and DRs per aspiration for IVF were 30.7 and 22.8%, respectively, and for 
      ICSI 29.7 and 20.0%, respectively. The PRs and DRs for FETs were 26.4 and 17.8%, 
      respectively. Multiple DR per PR were 22.2% for twins and 1.5% for triplets 
      following fresh IVF/ICSI and 16.4% for twins and 0.8% for triplets for FETs. 
      Ovarian hyperstimulation syndrome complicated >4585 cycles (0.6%). Access to ART 
      varied from 11 to 3988 cycles per million population. ICSI comprised 66.0% of all 
      initiated cycles, FET 27.4% and SET 20.7%. Perinatal mortality rate was 25.2 per 
      1000 births for fresh IVF/ICSI and 17.5 per 1000 for FETs. LIMITATIONS, REASONS 
      FOR CAUTION: 44.6% of the countries provided incomplete data. Quality of data 
      varies among individual countries and is dependant on the policy of the local 
      regulatory authority for monitoring ART clinics. Continuous efforts are needed to 
      improve comprehensiveness and quality of data collected. WIDER IMPLICATIONS OF 
      THE FINDINGS: Adopting the policy of SET, FET and the cessation of transferring 
      more than two embryos should be widely applied. ICMART will continue helping 
      countries and regions to establish their own ART registries. STUDY 
      FUNDING/COMPETING INTEREST(S): ICMART receives financial support from medical 
      societies: European Society for Human Reproduction and Embryology (ESHRE), 
      American Society for Reproduction Medicine (ASRM), Fertility Society of Australia 
      (FSA), Japan Society for Reproductive Medicine (JSRM), Latin American Network for 
      Reproductive Medicine (REDLARA) and Middle East Fertility Society (MEFS) and 
      Society for Assisted Reproductive Technology (SART). All authors have no conflict 
      of interest in relation to this work. We declare no support or financial 
      relationship with any organizations or any activities that could appear to have 
      influenced the submitted work.
FAU - Mansour, Ragaa
AU  - Mansour R
FAU - Ishihara, Osamu
AU  - Ishihara O
FAU - Adamson, G David
AU  - Adamson GD
FAU - Dyer, Silke
AU  - Dyer S
FAU - de Mouzon, Jacques
AU  - de Mouzon J
FAU - Nygren, Karl Gosta
AU  - Nygren KG
FAU - Sullivan, Elizabeth
AU  - Sullivan E
FAU - Zegers-Hochschild, Fernando
AU  - Zegers-Hochschild F
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140502
PL  - England
TA  - Hum Reprod
JT  - Human reproduction (Oxford, England)
JID - 8701199
SB  - IM
MH  - Cross-Sectional Studies
MH  - Embryo Transfer
MH  - Female
MH  - Humans
MH  - International Cooperation
MH  - Pregnancy
MH  - Pregnancy Outcome
MH  - Pregnancy Rate
MH  - Pregnancy, Multiple/statistics & numerical data
MH  - Premature Birth
MH  - Prevalence
MH  - Registries
MH  - Reproductive Techniques, Assisted/*standards/*statistics & numerical data
MH  - Retrospective Studies
MH  - Single Embryo Transfer
MH  - Sperm Injections, Intracytoplasmic
EDAT- 2014/05/06 06:00
MHDA- 2015/04/04 06:00
CRDT- 2014/05/06 06:00
PHST- 2014/05/06 06:00 [entrez]
PHST- 2014/05/06 06:00 [pubmed]
PHST- 2015/04/04 06:00 [medline]
AID - deu084 [pii]
AID - 10.1093/humrep/deu084 [doi]
PST - ppublish
SO  - Hum Reprod. 2014 Jul;29(7):1536-51. doi: 10.1093/humrep/deu084. Epub 2014 May 2.