PMID- 24797512 OWN - NLM STAT- MEDLINE DCOM- 20141229 LR - 20211021 IS - 1534-6307 (Electronic) IS - 1523-3774 (Linking) VI - 16 IP - 6 DP - 2014 Jun TI - Clinical relevance of beta(2)-glycoprotein-I plasma levels in antiphospholipid syndrome (APS). PG - 424 LID - 10.1007/s11926-014-0424-9 [doi] AB - Antiphospholipid syndrome (APS) is characterized by the presence of antiphospholipid (aPL) antibodies associated with thrombosis or pregnancy morbidity. The antibodies mainly involved in this disorder are directed against beta2-glycoprotein I (beta2-GPI). beta2-GPI plasma level is usually not reported in studies on APS, because it is not regarded as relevant to the diagnosis and prognosis of APS. Nevertheless its measurement may be important for understanding the pathophysiology of the syndrome. This review summarizes available data from the literature on plasma concentrations of beta2-GPI in patients with different antibody profiles. FAU - Banzato, Alessandra AU - Banzato A AD - Department of Cardiac Thoracic and Vascular Sciences, University of Padova, Via Giustiniani, 2, 35128, Padova, Italy, alessandra.banzato@unipd.it. FAU - Pengo, Vittorio AU - Pengo V LA - eng PT - Journal Article PT - Review PL - United States TA - Curr Rheumatol Rep JT - Current rheumatology reports JID - 100888970 RN - 0 (Antibodies, Antiphospholipid) RN - 0 (beta 2-Glycoprotein I) SB - IM MH - Antibodies, Antiphospholipid/blood MH - Antiphospholipid Syndrome/*blood/immunology MH - Humans MH - Thrombosis/blood/immunology MH - beta 2-Glycoprotein I/*blood/immunology EDAT- 2014/05/07 06:00 MHDA- 2014/12/30 06:00 CRDT- 2014/05/07 06:00 PHST- 2014/05/07 06:00 [entrez] PHST- 2014/05/07 06:00 [pubmed] PHST- 2014/12/30 06:00 [medline] AID - 10.1007/s11926-014-0424-9 [doi] PST - ppublish SO - Curr Rheumatol Rep. 2014 Jun;16(6):424. doi: 10.1007/s11926-014-0424-9.