PMID- 24797515
OWN - NLM
STAT- MEDLINE
DCOM- 20150713
LR  - 20141112
IS  - 1439-0396 (Electronic)
IS  - 0931-2439 (Linking)
VI  - 98
IP  - 6
DP  - 2014 Dec
TI  - Identification and differential distribution of CART in the small intestine 
      depending on the diet.
PG  - 1117-23
LID - 10.1111/jpn.12187 [doi]
AB  - This study was aimed at identifying and locating cocaine- and 
      amphetamine-regulated transcript (CART) in the small intestine of broilers in 
      relation to the diet. The feeding regime of the chicks was based on diets largely 
      consisting of maize and one of four protein sources: post-extraction soya bean 
      meal (SBM) or non-GM seed meal - meal from traditional variety of soy seeds 
      Glicine max (FFS) and meal from seeds of Lupinus angustifolius (LA) and Lupinus 
      luteus L (LY). The presence of cocaine- and amphetamine-regulated transcript 
      immunoreactive (CART-IR) in the wall of the small intestine of the chicks was 
      determined on the basis of staining patterns produced by the immunohistochemical 
      method (IHC). CART-IR structures were found in the myenteric plexus (MP), 
      submucosus plexus (SP), in endomucosal fibres, and fibres innervating miocytes 
      and blood vessels in the muscularis membrane and adipocytes of the white adipose 
      tissue (WAT) located on the perimeter of the serous membrane and single cells of 
      the diffuse neuroendocrine system. Based on microscopic observation and result 
      analysis, the lowest number of CART-IR structures was identified in the group 
      that was fed the SBM-based diet. This study confirms previous observations 
      concerning CART distribution in the gastrointestinal tract (GIT) of animal and 
      broadens current knowledge by inclusion of chicken in the list of CART-positive 
      species. Moreover, this work provides evidence that dietary composition can be a 
      factor that stimulates post-prandial CART secretion in intestinal nerve 
      structures.
CI  - Journal of Animal Physiology and Animal Nutrition (c) 2014 Blackwell Verlag GmbH.
FAU - Janiuk, I
AU  - Janiuk I
AD  - Department of Nutrition and Food Assessment, Institute of Health Sciences, 
      University of Natural Sciences and Humanities, Siedlce, Poland.
FAU - Olkowski, B
AU  - Olkowski B
FAU - Szczotka-Bochniarz, A
AU  - Szczotka-Bochniarz A
LA  - eng
PT  - Journal Article
DEP - 20140505
PL  - Germany
TA  - J Anim Physiol Anim Nutr (Berl)
JT  - Journal of animal physiology and animal nutrition
JID - 101126979
RN  - 0 (Nerve Tissue Proteins)
RN  - 0 (cocaine- and amphetamine-regulated transcript protein)
SB  - IM
MH  - Animal Feed/*analysis
MH  - Animal Nutritional Physiological Phenomena
MH  - Animals
MH  - Chickens/*metabolism
MH  - Diet/*veterinary
MH  - Gene Expression Regulation/physiology
MH  - Intestine, Small/*metabolism
MH  - Nerve Tissue Proteins/genetics/*metabolism
OTO - NOTNLM
OT  - broiler
OT  - cocaine- and amphetamine-related transcript
OT  - lupines
OT  - small intestine
OT  - soya bean
EDAT- 2014/05/07 06:00
MHDA- 2015/07/15 06:00
CRDT- 2014/05/07 06:00
PHST- 2013/10/09 00:00 [received]
PHST- 2014/02/28 00:00 [accepted]
PHST- 2014/05/07 06:00 [entrez]
PHST- 2014/05/07 06:00 [pubmed]
PHST- 2015/07/15 06:00 [medline]
AID - 10.1111/jpn.12187 [doi]
PST - ppublish
SO  - J Anim Physiol Anim Nutr (Berl). 2014 Dec;98(6):1117-23. doi: 10.1111/jpn.12187. 
      Epub 2014 May 5.