PMID- 24797981
OWN - NLM
STAT- MEDLINE
DCOM- 20150413
LR  - 20191210
IS  - 1898-4002 (Electronic)
IS  - 1896-1126 (Linking)
VI  - 59
IP  - 1
DP  - 2014 Mar
TI  - Evaluation of estrogen receptor-beta expression in the epithelium of the oral mucosa 
      in menopausal women under hormone replacement therapy.
PG  - 85-9
LID - S1896-1126(14)00026-1 [pii]
LID - 10.1016/j.advms.2013.09.003 [doi]
AB  - PURPOSE: We aimed to evaluate the ERbeta expression in the epithelium of the oral 
      mucosa in menopausal women treated with oral, transdermal or local (vaginal) 
      menopausal hormone therapy. MATERIAL/METHODS: In this study, we included 60 women 
      treated with oral, transdermal or vaginal menopausal hormone therapy. The study 
      material was obtained from swabs taken from the buccal mucosa before 
      administering HRT, and after 6 weeks, 3 months, 6 months and 12 months of 
      therapy. We assessed estrogen receptor-beta (ERbeta) expression levels in subsequent 
      swabs by immunohistochemical analysis. RESULTS: The highest increase in the ERbeta 
      expression was observed after 3 months of oral and transdermal hormone therapy. 
      CONCLUSIONS: Oral and transdermal HRT may be an effective method of treatment of 
      oral discomfort in menopausal women.
CI  - Copyright (c) 2014 Medical University of Bialystok. Published by Elsevier Urban & 
      Partner Sp. z o.o. All rights reserved.
FAU - Sawczuk, Beata
AU  - Sawczuk B
AD  - Department of Prosthodontics, Medical University of Bialystok, Bialystok, Poland. 
      Electronic address: beata.sawczuk@wp.pl.
FAU - Golebiewska, Maria
AU  - Golebiewska M
AD  - Department of Prosthodontics, Medical University of Bialystok, Bialystok, Poland.
FAU - Mazurek, Andrzej
AU  - Mazurek A
AD  - Department of Gynecology, Medical University of Bialystok, Bialystok, Poland.
FAU - Chyczewski, Lech
AU  - Chyczewski L
AD  - Department of Medical Pathomorphology, Medical University of Bialystok, 
      Bialystok, Poland.
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140329
PL  - Netherlands
TA  - Adv Med Sci
JT  - Advances in medical sciences
JID - 101276222
RN  - 0 (Estrogen Receptor beta)
SB  - IM
MH  - Epithelium/drug effects/*metabolism
MH  - Estrogen Receptor beta/*metabolism
MH  - Female
MH  - Follow-Up Studies
MH  - *Hormone Replacement Therapy
MH  - Humans
MH  - Immunoenzyme Techniques
MH  - Menopause/*drug effects
MH  - Middle Aged
MH  - Mouth Mucosa/cytology/drug effects/*metabolism
OTO - NOTNLM
OT  - Estrogen receptor
OT  - Menopause
OT  - Oral mucosa
EDAT- 2014/05/07 06:00
MHDA- 2015/04/14 06:00
CRDT- 2014/05/07 06:00
PHST- 2012/11/22 00:00 [received]
PHST- 2013/09/03 00:00 [accepted]
PHST- 2014/05/07 06:00 [entrez]
PHST- 2014/05/07 06:00 [pubmed]
PHST- 2015/04/14 06:00 [medline]
AID - S1896-1126(14)00026-1 [pii]
AID - 10.1016/j.advms.2013.09.003 [doi]
PST - ppublish
SO  - Adv Med Sci. 2014 Mar;59(1):85-9. doi: 10.1016/j.advms.2013.09.003. Epub 2014 Mar 
      29.