PMID- 24799793
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20140506
LR  - 20211021
IS  - 0974-620X (Print)
IS  - 0974-7842 (Electronic)
IS  - 0974-620X (Linking)
VI  - 7
IP  - 1
DP  - 2014 Jan
TI  - Optical coherence tomographic assessment of retinal nerve fiber layer thickness 
      changes before and after glaucoma filtration surgery.
PG  - 3-8
LID - 10.4103/0974-620X.127910 [doi]
AB  - BACKGROUND: Glaucomatous Optic Neuropathy (GON) is very common in the glaucoma 
      patients, and impaired effect of glaucoma is measured by the Retinal Nerve Fiber 
      Layer (RNFL) thickness. OBJECTIVE: The study was conducted to find out the mean 
      RNFL thickness, RNFL thickness in different quadrants, Intra-Ocular Pressure 
      (IOP) changes, and visual field changes after filtration surgery in different 
      ages and genders using Optical Coherence Tomography (OCT). MATERIALS AND METHODS: 
      The study was an interventional case-series conducted at the Glaucoma Clinic at 
      the Regional Institute of Ophthalmology at Kolkata from March 2009 to August 
      2010. Fifty-one eyes of 43 open angle glaucoma patients had been selected for 
      clinical and ophthalmologic evaluation. All the eyes of glaucoma patients who 
      fulfilled the inclusion criteria were registered in the study population. The 
      glaucoma filtration surgery was done in these patients. The RNFL thickness, IOP, 
      visual field changes were measured before and after intervention of filtration 
      surgery. Pre-operative OCT images of RNFL were obtained 0 to 120 days before 
      surgery, and post-operative images were obtained from 60 to 120 days after 
      surgery. Data collected in a standard data collection form included schedule. 
      RESULTS: Paired t-test was used. RNFL thickness was (pre-operative: 52.56 +/- 
      17.40, post-operative: 58.48 +/- 20.20, P < 0.0001) significantly increased after 
      filtration surgery measured by OCT with significant reduction of IOP (r = - 0.38, 
      P = 0.005) irrespective of age and gender. CONCLUSIONS: An increase in RNFL 
      thickness was observed after glaucoma filtration surgery that correlated with IOP 
      reduction.
FAU - Sarkar, Kumaresh Chandra
AU  - Sarkar KC
AD  - Department of Ophthalmology, Calcutta National Medical College, Kolkata, West 
      Bengal, India.
FAU - Das, Palash
AU  - Das P
AD  - Department of Community Medicine, Midnapore Medical College, Paschim Medinipur, 
      West Bengal, India.
FAU - Pal, Ranabir
AU  - Pal R
AD  - Department of Community Medicine and Family Medicine, AIIMS, Jodhpur, India.
FAU - Shaw, Chattaranjan
AU  - Shaw C
AD  - Department of Ophthalmology, RIO, Medical College, Kolkata, West Bengal, India.
LA  - eng
PT  - Journal Article
PL  - India
TA  - Oman J Ophthalmol
JT  - Oman journal of ophthalmology
JID - 101519430
PMC - PMC4008898
OTO - NOTNLM
OT  - Glaucomatous optic neuropathy
OT  - optical coherence tomography
OT  - retinal nerve fiber layer thickness
COIS- Conflict of Interest: None declared.
EDAT- 2014/05/07 06:00
MHDA- 2014/05/07 06:01
PMCR- 2014/01/01
CRDT- 2014/05/07 06:00
PHST- 2014/05/07 06:00 [entrez]
PHST- 2014/05/07 06:00 [pubmed]
PHST- 2014/05/07 06:01 [medline]
PHST- 2014/01/01 00:00 [pmc-release]
AID - OJO-7-3 [pii]
AID - 10.4103/0974-620X.127910 [doi]
PST - ppublish
SO  - Oman J Ophthalmol. 2014 Jan;7(1):3-8. doi: 10.4103/0974-620X.127910.