PMID- 24800475
OWN - NLM
STAT- MEDLINE
DCOM- 20140723
LR  - 20170310
IS  - 0022-9040 (Print)
IS  - 0022-9040 (Linking)
VI  - 53
IP  - 12
DP  - 2013
TI  - [First Moscow "snapshot" register of acute coronary syndromes: characteristics of 
      patients, management and outcomes during hospitalization].
PG  - 4-13
AB  - AIM: To characterize inhospital management of patients (pts) with acute coronary 
      syndromes (ACS) using data from Moscow snapshot registry of hospitalized pts with 
      ACS. METHODS: The registry included data on consecutive pts with ACS hospitalized 
      with label ACS in coronary care units (CCU) or equivalents within 24 hours (h) 
      after onset of symptoms during one week in November 2013. Data was obtained from 
      32 (17 percutaneous coronary intervention [PCI] capable or "invasive") city 
      hospitals officially treating ACS patients. RESULTS: Total number of pts--584 
      (mean age 66.4 +/- 13.1 years; > or = 65 years 54.6%; women 44.2%; registered in 
      invasive hospital--42%). Portions of pts labeled ST-elevation (STE) and non 
      ST-elevation (NSTE) ACS--27.9 and 72.1%, respectively. Portion of pts 
      hospitalized within 1-st 12 h after symptoms onset--65.2% (68% among STEACS pts). 
      Reperfusion therapy--44.8% of pts with STEACS (54.3% in invasive and 21.3% in 
      noninvasive hospitals, p < 0.0001). Thrombolysis (TI) was performed in 19% of 
      STEACS pts (41.9% prehospital). In hospital median admission to initiation of TI 
      time--0.30 h (quartiles I-III 0.15-0.30 h). Rate of primary (p) PCI in STEACS 
      pts--overall 25.8%, in invasive hospitals--36.2%, in pts admitted within 12 
      h--31.4 and 40.5%, respectively. Median admission--pPCI initiation time--1.35 h 
      (quartiles I-III 1.00- 2.15 h). PCI rate among NSTEACS pts--6.2 overall and 20.5% 
      in invasive hospitals (14.7% during 1st 72 h). Medication in hospital: 
      aspirin--95.2, clopidogrel--70.7, ticagrelor--4.3%, parenteral 
      anticoagulants--88.9 (1/3 unfractionated heparin [UFH] subcutaneously), ACE 
      inhibitors--83.3, beta-blockers--86.3, statins--58.3%. Mean duration of hospital 
      stay--13.2 +/- 4.4 days. Transferral from noninvasive to invasive hospital for 
      urgent coronary intervention--4.5 and 3.5% of STE and NSTE ACS pts, respectively. 
      Hospital mortality--12.4 and 1.9% among pts registered as STE and NSTEACS, 
      respectively. Cardiac troponins measured--42% (39% among STEACS) pts. CONCLUSION: 
      The following features of inhospital management of pts diagnosed as ACS at CCU 
      (or its equivalent) admission could be object of improvement: low rate of 
      reperfusion therapy and use of PCI, long interval between admission and 
      initiation of PCI, insufficient use of some standard medications, frequent use of 
      subcutaneous UFH, rare transferal of PCI eligible pts from noninvasive to 
      invasive hospitals. However existing management was associated with reported low 
      hospital mortality in patients labeled as NSTEACS.
FAU - Erlikh, A D
AU  - Erlikh AD
FAU - Matskeplishvili, S T
AU  - Matskeplishvili ST
FAU - Gratsianskii, N A
AU  - Gratsianskii NA
FAU - Buziashvili, Iu I
AU  - Buziashvili IuI
LA  - rus
PT  - English Abstract
PT  - Journal Article
PL  - Russia (Federation)
TA  - Kardiologiia
JT  - Kardiologiia
JID - 0376351
RN  - 0 (Cardiovascular Agents)
SB  - IM
MH  - *Acute Coronary Syndrome/diagnosis/epidemiology/therapy
MH  - Aged
MH  - Cardiovascular Agents/*therapeutic use
MH  - Coronary Care Units/methods/statistics & numerical data
MH  - Female
MH  - Health Services Needs and Demand
MH  - Hospitalization/statistics & numerical data
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Moscow/epidemiology
MH  - *Percutaneous Coronary Intervention/methods/statistics & numerical data
MH  - Registries/*statistics & numerical data
EDAT- 2013/01/01 00:00
MHDA- 2014/07/24 06:00
CRDT- 2014/05/08 06:00
PHST- 2014/05/08 06:00 [entrez]
PHST- 2013/01/01 00:00 [pubmed]
PHST- 2014/07/24 06:00 [medline]
PST - ppublish
SO  - Kardiologiia. 2013;53(12):4-13.