PMID- 24805993
OWN - NLM
STAT- MEDLINE
DCOM- 20151102
LR  - 20211021
IS  - 1573-3521 (Electronic)
IS  - 0160-7715 (Linking)
VI  - 37
IP  - 6
DP  - 2014 Dec
TI  - What keeps a body moving? The brain-derived neurotrophic factor val66met 
      polymorphism and intrinsic motivation to exercise in humans.
PG  - 1180-92
LID - 10.1007/s10865-014-9567-4 [doi]
AB  - Individuals who are intrinsically motivated to exercise are more likely to do so 
      consistently. In previous research, those with at least one copy of the 
      methionine (met) allele in the brain-derived neurotrophic factor gene (BDNF; 
      rs6265) had greater increases in positive mood and lower perceived exertion 
      during exercise. This study examined whether genotype for BDNF is also related to 
      intrinsic motivation, measured by self-report during a treadmill exercise session 
      and a free-choice behavioral measure (continuing to exercise given the option to 
      stop) among 89 regular exercisers (age M = 23.58, SD = 3.95). Those with at least 
      one copy of the met allele reported greater increases in intrinsic motivation 
      during exercise and were more likely to continue exercising when given the option 
      to stop (55 vs. 33%). Results suggest that underlying genetic factors may 
      partially influence perceptions of inherent rewards associated with exercise and 
      might inform the development of individually targeted interventions.
FAU - Caldwell Hooper, Ann E
AU  - Caldwell Hooper AE
AD  - Department of Psychology, University of New Mexico, Albuquerque, NM, USA, 
      anncwell@gmail.com.
FAU - Bryan, Angela D
AU  - Bryan AD
FAU - Hagger, Martin S
AU  - Hagger MS
LA  - eng
PT  - Journal Article
DEP - 20140508
PL  - United States
TA  - J Behav Med
JT  - Journal of behavioral medicine
JID - 7807105
RN  - 0 (Brain-Derived Neurotrophic Factor)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Affect
MH  - Alleles
MH  - Brain-Derived Neurotrophic Factor/*genetics/*physiology
MH  - Exercise/*physiology/*psychology
MH  - Female
MH  - Genotype
MH  - Humans
MH  - Male
MH  - Motivation/*genetics
MH  - Polymorphism, Single Nucleotide/*genetics
MH  - Young Adult
EDAT- 2014/05/09 06:00
MHDA- 2015/11/03 06:00
CRDT- 2014/05/09 06:00
PHST- 2013/08/09 00:00 [received]
PHST- 2014/04/16 00:00 [accepted]
PHST- 2014/05/09 06:00 [entrez]
PHST- 2014/05/09 06:00 [pubmed]
PHST- 2015/11/03 06:00 [medline]
AID - 10.1007/s10865-014-9567-4 [doi]
PST - ppublish
SO  - J Behav Med. 2014 Dec;37(6):1180-92. doi: 10.1007/s10865-014-9567-4. Epub 2014 
      May 8.