PMID- 24811490
OWN - NLM
STAT- MEDLINE
DCOM- 20150119
LR  - 20240109
IS  - 1520-5118 (Electronic)
IS  - 0021-8561 (Linking)
VI  - 62
IP  - 22
DP  - 2014 Jun 4
TI  - Nontargeted detection of adulteration of skim milk powder with foreign proteins 
      using UHPLC-UV.
PG  - 5198-206
LID - 10.1021/jf404924x [doi]
AB  - Chromatographic profiles of skim milk powder (SMP) and mixtures of SMP with soy 
      (SPI), pea (PPI), brown rice (BRP), and hydrolyzed wheat protein (HWPI) isolates 
      were obtained by ultrahigh-performance liquid chromatography (UHPLC) with 215 nm 
      detection. Two data analysis approaches were compared for their utility to 
      classify samples as authentic or adulterated. The t test approach evaluated data 
      points exceeding the 99% confidence limit of the mean authentic SMP chromatogram 
      and used data points from the entire chromatogram. The other approach used the 
      multivariate Q statistic from a SIMCA model of authentic samples to determine 
      adulteration and used a selected retention window to obtain best classifications. 
      Q-Statistic and t test correctly classified adulteration of SMP with SPI at the 
      1% and 3% levels, respectively, while minimizing false classifications of 
      authentic SMP. Detection of SMP adulterated with PPI, BRP, and HWPI was possible 
      at higher adulteration levels.
FAU - Jablonski, Joseph E
AU  - Jablonski JE
AD  - Center for Food Safety and Applied Nutrition, Division of Food Processing Science 
      and Technology, U.S. Food and Drug Administration , 6502 South Archer Road, 
      Bedford Park, Illinois 60501, United States.
FAU - Moore, Jeffrey C
AU  - Moore JC
FAU - Harnly, James M
AU  - Harnly JM
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
DEP - 20140520
PL  - United States
TA  - J Agric Food Chem
JT  - Journal of agricultural and food chemistry
JID - 0374755
RN  - 0 (Plant Proteins)
RN  - 0 (Powders)
SB  - IM
MH  - Animals
MH  - Cattle
MH  - Chromatography, High Pressure Liquid/instrumentation/*methods
MH  - Food Contamination/*analysis
MH  - Milk/*chemistry
MH  - Oryza/chemistry
MH  - Pisum sativum/chemistry
MH  - Plant Proteins/*analysis
MH  - Powders/*chemistry
MH  - Glycine max/chemistry
MH  - Triticum/chemistry
EDAT- 2014/05/09 06:00
MHDA- 2015/01/20 06:00
CRDT- 2014/05/10 06:00
PHST- 2014/05/10 06:00 [entrez]
PHST- 2014/05/09 06:00 [pubmed]
PHST- 2015/01/20 06:00 [medline]
AID - 10.1021/jf404924x [doi]
PST - ppublish
SO  - J Agric Food Chem. 2014 Jun 4;62(22):5198-206. doi: 10.1021/jf404924x. Epub 2014 
      May 20.