PMID- 24818951
OWN - NLM
STAT- MEDLINE
DCOM- 20151123
LR  - 20150309
IS  - 2048-8734 (Electronic)
IS  - 2048-8726 (Linking)
VI  - 4
IP  - 1
DP  - 2015 Feb
TI  - Outcomes following primary percutaneous coronary intervention in the setting of 
      cardiac arrest: a registry database study.
PG  - 6-15
LID - 10.1177/2048872614534079 [doi]
AB  - BACKGROUND: The mortality rate among patients undergoing primary percutaneous 
      coronary intervention (PPCI) in the setting of cardiac arrest (CA) and whether 
      the location where the patient sustains CA influences the outcome is not known in 
      the contemporary era. METHODS: Prospectively collected data at a tertiary cardiac 
      centre on all patients undergoing PPCI for ST elevation myocardial infarction 
      (STEMI) in the setting of CA was analysed. RESULTS: In total, 484/4118 (11.8%) 
      patients sustained CA during the study period. Of these, 91/484 (18.8%) sustained 
      CA prior to ambulance arrival, the remainder occurred either after ambulance 
      arrival or in hospital. The overall in-hospital mortality was 20.5% in this 
      cohort. Those sustaining CA before ambulance arrival experienced the highest 
      unadjusted mortality compared to those that had CA after ambulance arrival, in 
      hospital and in the catheterisation laboratory (29.7% versus 12.0%, 16.1% and 
      23.8% respectively, p=0.03). Multiple logistic regression analysis showed that 
      the following parameters are independent predictors of in-hospital mortality: age 
      (odds ratio (OR) for each year increment of age 1.05; 95% confidence interval 
      (CI) 1.02-1.08, p=0.0009); female gender (OR 2.42; 95% CI 1.17-4.99, p=0.0173); 
      previous PCI (OR 7.59; 95% CI 1.72-33.53, p=0.0075); asystole/ electromechanical 
      dissociation (EMD) (OR 13.43; 95% CI 5.34-33.80, p<0.0001); and patient location 
      at arrest (OR 5.77 for before ambulance arrival; 95% CI 2.55-13.07, p<0.0001). 
      CONCLUSIONS: In conclusion, in-hospital mortality remains high among patients 
      undergoing PPCI in the context of CA, particularly among those that arrest prior 
      to ambulance arrival.
CI  - (c) The European Society of Cardiology 2014.
FAU - Kunadian, Vijay
AU  - Kunadian V
AD  - Institute of Cellular Medicine, Newcastle University, UK Freeman Hospital, 
      Newcastle upon Tyne Hospitals NHS Foundation Trust, UK 
      vijay.kunadian@newcastle.ac.uk.
FAU - Bawamia, Bilal
AU  - Bawamia B
AD  - Institute of Cellular Medicine, Newcastle University, UK Freeman Hospital, 
      Newcastle upon Tyne Hospitals NHS Foundation Trust, UK.
FAU - Maznyczka, Annette
AU  - Maznyczka A
AD  - Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, UK.
FAU - Zaman, Azfar
AU  - Zaman A
AD  - Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, UK.
FAU - Qiu, Weiliang
AU  - Qiu W
AD  - Channing Division of Network Medicine, Brigham and Women's Hospital/Harvard 
      Medical School, USA.
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20140512
PL  - England
TA  - Eur Heart J Acute Cardiovasc Care
JT  - European heart journal. Acute cardiovascular care
JID - 101591369
SB  - IM
MH  - Cardiopulmonary Resuscitation
MH  - Coronary Angiography/mortality/statistics & numerical data
MH  - Coronary Care Units/statistics & numerical data
MH  - Female
MH  - Heart Arrest/*complications/mortality
MH  - Hospital Mortality
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/mortality/*surgery
MH  - Percutaneous Coronary Intervention/*mortality
MH  - Prospective Studies
MH  - Registries
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Cardiac arrest
OT  - asystole
OT  - mortality
OT  - primary percutaneous coronary intervention
EDAT- 2014/05/14 06:00
MHDA- 2015/12/15 06:00
CRDT- 2014/05/14 06:00
PHST- 2014/05/14 06:00 [entrez]
PHST- 2014/05/14 06:00 [pubmed]
PHST- 2015/12/15 06:00 [medline]
AID - 2048872614534079 [pii]
AID - 10.1177/2048872614534079 [doi]
PST - ppublish
SO  - Eur Heart J Acute Cardiovasc Care. 2015 Feb;4(1):6-15. doi: 
      10.1177/2048872614534079. Epub 2014 May 12.