PMID- 24822230 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20140513 LR - 20211021 IS - 2322-4436 (Print) IS - 2322-3219 (Electronic) IS - 2322-3219 (Linking) VI - 2 IP - 4 DP - 2013 Winter TI - The protective effect of phaseolus vulgaris on cataract in type 2 diabetes: a profitable hypothesis. PG - 105-8 AB - The pathophysiology of major ocular complications in type 2 diabetes mellitus (T2DM) among Bantu is not well understood. Several studies have been conducted to determine the basic reasons of visual deficiencies (VD) (blindness, visual impairment, and ocular eye diseases) in T2DM among Bantu from Central Africa. The quality of dietary intake was assessed in patients along with other ophthalmological assessments for diabetic retinopathy, cataract, glaucoma, and macular edema. Beans (Phaseolus vulgaris) and leafy vegetables are rich in antioxidants. The consumption of at least 3 ladles per meal, 3 times or more per week, has been identified as a potential protective factor against cataract. The anti-radical activity of beans is well known in the literature. Beans are considered to have a comparatively higher antioxidant activity than in many other vegetables. Our findings from previous epidemiologic studies establish that the antioxidant activity of P. vulgaris helps control blood glucose. We, therefore, hypothesize that the dietary supplements of bean can be a low-cost prevention approach to reduce cataract and much other visual comorbidity associated with T2DM. However, further epidemiological studies combined with molecular research need to be conducted to prove this hypothesis. FAU - Longo-Mbenza, Benjamin AU - Longo-Mbenza B AD - Walter Sisulu University, Faculty of Health Sciences, South Africa. FAU - Muaka, Moisemvitu AU - Muaka M AD - University of Kinshasa, Faculty of Medicine Service of Ophthalmology, Kinshasa, Democratic Republic of the Congo. LA - eng PT - Journal Article PL - United States TA - Med Hypothesis Discov Innov Ophthalmol JT - Medical hypothesis, discovery & innovation ophthalmology journal JID - 101611331 PMC - PMC4017630 OTO - NOTNLM OT - Anti-radical Activity OT - Antioxidant OT - Cataract OT - Diabetes Mellitus OT - Phaseolus vulgaris OT - Visual deficiencies EDAT- 2013/01/01 00:00 MHDA- 2013/01/01 00:01 PMCR- 2013/12/01 CRDT- 2014/05/14 06:00 PHST- 2014/05/14 06:00 [entrez] PHST- 2013/01/01 00:00 [pubmed] PHST- 2013/01/01 00:01 [medline] PHST- 2013/12/01 00:00 [pmc-release] AID - mehdiophth-2-105 [pii] PST - ppublish SO - Med Hypothesis Discov Innov Ophthalmol. 2013 Winter;2(4):105-8.