PMID- 24822448
OWN - NLM
STAT- MEDLINE
DCOM- 20150901
LR  - 20190923
IS  - 1000-8713 (Print)
IS  - 1000-8713 (Linking)
VI  - 32
IP  - 2
DP  - 2014 Feb
TI  - [Simultaneous determination of 16 organic acids in feed additives by on-line 
      enrichment and ion chromatography-mass spectrometry].
PG  - 145-50
AB  - A novel analytical method for simultaneous determination of sixteen organic acids 
      by on-line enrichment and ion chromatography-mass spectrometry (IC-MS) was 
      developed. Online enrichment and separation of the organic acids were performed 
      by ion chromatography on a homemade enrichment column and a homemade separation 
      column. The qualitative and quantitative analyses of the organic acids were 
      performed by mass spectrometry in selected ion monitoring (SIM) mode on the basis 
      of atmospheric pressure chemical ionization (APCI) source in negative mode. The 
      sample of 200 microL was injected for the analysis, and the on-line enrichment 
      time was 3 min. The sodium hydroxide solution was used as a gradient elution 
      system. The two columns made it possible to have a low limit of detection due to 
      the good enrichment and separation capability. The sixteen organic acids were 
      separated completely within 30 min. All curves showed good linearity within the 
      test concentration ranges. The limits of detection (LODs) were between 0.01 and 
      0.22 mg/L, and the average recoveries were between 70.6% and 110.8%. The relative 
      standard deviations (RSDs) were less than 6.3%. The results indicate that this 
      method is simple, rapid, sensitive and accurate for the determination of the 
      organic acids in feed additives.
FAU - Xiong, Zhiyu
AU  - Xiong Z
FAU - Dong, Ying
AU  - Dong Y
FAU - Zhou, Hongbin
AU  - Zhou H
FAU - Yu, Yang
AU  - Yu Y
FAU - Li, Jing
AU  - Li J
FAU - Sun, Li
AU  - Sun L
LA  - chi
PT  - Journal Article
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 0 (Acids)
RN  - 0 (Organic Chemicals)
SB  - IM
MH  - Acids/*analysis
MH  - Animal Feed/*analysis
MH  - Atmospheric Pressure
MH  - Chromatography
MH  - *Chromatography, High Pressure Liquid
MH  - Limit of Detection
MH  - *Mass Spectrometry
MH  - Organic Chemicals
MH  - Spectrum Analysis
EDAT- 2014/05/16 06:00
MHDA- 2015/09/02 06:00
CRDT- 2014/05/15 06:00
PHST- 2014/05/15 06:00 [entrez]
PHST- 2014/05/16 06:00 [pubmed]
PHST- 2015/09/02 06:00 [medline]
AID - 10.3724/sp.j.1123.2013.10003 [doi]
PST - ppublish
SO  - Se Pu. 2014 Feb;32(2):145-50. doi: 10.3724/sp.j.1123.2013.10003.