PMID- 2482742
OWN - NLM
STAT- MEDLINE
DCOM- 19900323
LR  - 20041117
IS  - 0167-5699 (Print)
IS  - 0167-5699 (Linking)
VI  - 10
IP  - 12
DP  - 1989 Dec
TI  - Characterizing T-cell epitopes in vaccine candidates.
PG  - 408-9
AB  - T-cell clones can be used to test in vitro whether synthetic peptides associate 
      with major histocompatibility complex (MHC) antigens - a necessary condition for 
      the peptides to be immunogenic. Generally, the T-cell clones have been obtained 
      from immune donors, but J.R.L. Pink and F. Sinigaglia argue here that non-immune, 
      human leukocyte antigen (HLA)-typed donors are a useful source of clones and 
      antigen-presenting cells that can be used to assay systematically peptide-MHC 
      associations.
FAU - Pink, J R
AU  - Pink JR
FAU - Sinigaglia, F
AU  - Sinigaglia F
LA  - eng
PT  - Journal Article
PL  - England
TA  - Immunol Today
JT  - Immunology today
JID - 8008346
RN  - 0 (Epitopes)
RN  - 0 (HLA Antigens)
RN  - 0 (Peptide Fragments)
RN  - 0 (Vaccines)
SB  - IM
MH  - Animals
MH  - Antigen-Presenting Cells/immunology
MH  - Cross Reactions
MH  - Epitopes/*immunology
MH  - Guinea Pigs
MH  - HLA Antigens/immunology
MH  - Humans
MH  - Immunization
MH  - Peptide Fragments/chemical synthesis/immunology
MH  - Protein Binding
MH  - T-Lymphocytes/*immunology
MH  - Vaccines/*immunology
EDAT- 1989/12/01 00:00
MHDA- 1989/12/01 00:01
CRDT- 1989/12/01 00:00
PHST- 1989/12/01 00:00 [pubmed]
PHST- 1989/12/01 00:01 [medline]
PHST- 1989/12/01 00:00 [entrez]
AID - 0167-5699(89)90037-6 [pii]
AID - 10.1016/0167-5699(89)90037-6 [doi]
PST - ppublish
SO  - Immunol Today. 1989 Dec;10(12):408-9. doi: 10.1016/0167-5699(89)90037-6.