PMID- 24828136 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20140622 LR - 20240330 IS - 1869-6953 (Print) IS - 1869-6961 (Electronic) IS - 1869-6961 (Linking) VI - 5 IP - 1 DP - 2014 Jun TI - Insulin Degludec Aspart: The First Co-formulation of Insulin Analogues. PG - 65-72 LID - 10.1007/s13300-014-0067-x [doi] AB - Insulin degludec/insulin aspart (IDegAsp) is the first soluble co-formulation which combines two insulin analogues, and provides effective basal and prandial glycemic coverage. It has been assessed as basal insulin in type 2 diabetes mellitus (T2DM), and as part of basal-bolus regime in both type 1 diabetes mellitus and T2DM. Insulin degludec has also been assessed as flexibly administered basal insulin in terms of time of administration. This review discusses data pertaining to the efficacy, safety, tolerability, and clinical potential of IDegAsp. The discussion includes comparisons of IDegAsp with basal as well as premixed insulin. FAU - Kalra, Sanjay AU - Kalra S AD - Department of Endocrinology, Bharti Hospital and BRIDE, Karnal, 132001, Haryana, India, brideknl@gmail.com. LA - eng PT - Journal Article DEP - 20140515 PL - United States TA - Diabetes Ther JT - Diabetes therapy : research, treatment and education of diabetes and related disorders JID - 101539025 PMC - PMC4065296 EDAT- 2014/05/16 06:00 MHDA- 2014/05/16 06:01 PMCR- 2014/05/15 CRDT- 2014/05/16 06:00 PHST- 2013/12/17 00:00 [received] PHST- 2014/05/16 06:00 [entrez] PHST- 2014/05/16 06:00 [pubmed] PHST- 2014/05/16 06:01 [medline] PHST- 2014/05/15 00:00 [pmc-release] AID - 67 [pii] AID - 10.1007/s13300-014-0067-x [doi] PST - ppublish SO - Diabetes Ther. 2014 Jun;5(1):65-72. doi: 10.1007/s13300-014-0067-x. Epub 2014 May 15.