PMID- 24828840 OWN - NLM STAT- MEDLINE DCOM- 20150309 LR - 20161125 IS - 1097-4598 (Electronic) IS - 0148-639X (Linking) VI - 51 IP - 1 DP - 2015 Jan TI - Load-controlled moderate and high-intensity resistance training programs provoke similar strength gains in young women. PG - 92-101 LID - 10.1002/mus.24271 [doi] AB - INTRODUCTION: While current exercise guidelines recommend progressive, high-intensity resistance training (RT) to promote muscle hypertrophy and strength gains, controversy exists regarding the efficacy of lighter-load RT. We compared 2 work-matched RT interventions that differed in training intensity. METHODS: Fifteen women underwent 10 weeks of unilateral knee extensor RT. One leg was trained at increasing intensity (intensity leg, InL, 50-80% 1-repetition maximum [1-RM]), and training progression in the contralateral leg (volume leg, VoL, 50% 1-RM) was based on increasing training volumes. Quadriceps muscle size (ultrasound, dual energy X-ray absorptiometry) and strength (isokinetic dynamometry) were assessed on 4 occasions. RESULTS: Both training programs induced significant, yet comparable increases in muscle size (InL: +4.6-12%, VoL: +3.1-11%) and strength (InL: +10-16%, VoL: +10-14%). CONCLUSIONS: Training at lower than commonly suggested intensities may be an equally effective alternative form of RT. Factors other than training intensity, such as the total mechanical work during training, may strongly affect the training response. CI - (c) 2014 Wiley Periodicals, Inc. FAU - Alegre, Luis M AU - Alegre LM AD - University of Castilla-La Mancha, Human and Sports Biomechanics Research Group, Toledo, Spain. FAU - Aguado, Xavier AU - Aguado X FAU - Rojas-Martin, Diego AU - Rojas-Martin D FAU - Martin-Garcia, Maria AU - Martin-Garcia M FAU - Ara, Ignacio AU - Ara I FAU - Csapo, Robert AU - Csapo R LA - eng PT - Journal Article DEP - 20141124 PL - United States TA - Muscle Nerve JT - Muscle & nerve JID - 7803146 SB - IM MH - Absorptiometry, Photon MH - Body Composition MH - Female MH - Healthy Volunteers MH - Humans MH - Isometric Contraction/*physiology MH - Longitudinal Studies MH - Muscle Strength/*physiology MH - Muscle, Skeletal/diagnostic imaging/*physiology MH - *Resistance Training MH - Statistics, Nonparametric MH - Thigh/innervation MH - Time Factors MH - Ultrasonography MH - Young Adult OTO - NOTNLM OT - DXA OT - hypertrophy OT - quadriceps femoris OT - strength training OT - ultrasound EDAT- 2014/05/16 06:00 MHDA- 2015/03/10 06:00 CRDT- 2014/05/16 06:00 PHST- 2013/12/17 00:00 [received] PHST- 2014/04/18 00:00 [revised] PHST- 2014/04/26 00:00 [accepted] PHST- 2014/05/16 06:00 [entrez] PHST- 2014/05/16 06:00 [pubmed] PHST- 2015/03/10 06:00 [medline] AID - 10.1002/mus.24271 [doi] PST - ppublish SO - Muscle Nerve. 2015 Jan;51(1):92-101. doi: 10.1002/mus.24271. Epub 2014 Nov 24.