PMID- 24834225
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20140516
LR  - 20220316
IS  - 2008-2258 (Print)
IS  - 2008-4234 (Electronic)
IS  - 2008-2258 (Linking)
VI  - 5
IP  - 4
DP  - 2012 Fall
TI  - Non-Helicobacter pylori, non-NSAIDs peptic ulcers: a descriptive study on 
      patients referred to Taleghani hospital with upper gastrointestinal bleeding.
PG  - 190-6
AB  - AIM: The purpose of the present study was to evaluate the number and proportion 
      of various causes of upper gastrointestinal bleeding and actual numbers of 
      non-NSAID, non-Helicobacter pylori (H.pylori) peptic ulcers seen in endoscopy of 
      these patients. BACKGROUND: The number and the proportion of patients with non- 
      H.pylori, non-NSAIDs peptic ulcer disease leading to upper gastrointestinal 
      bleeding is believed to be increasing after eradication therapy for H.pylori. 
      PATIENTS AND METHODS: Medical records of patients referred to the emergency room 
      of Taleghani hospital from 2010 with a clinical diagnosis of upper 
      gastrointestinal bleeding (hematemesis, coffee ground vomiting and melena) were 
      included in this study. Patients with hematochezia with evidence of a source of 
      bleeding from upper gastrointestinal tract in endoscopy were also included in 
      this study. RESULTS: In this study, peptic ulcer disease (all kinds of ulcers) 
      was seen in 61 patients which were about 44.85% of abnormalities seen on 
      endoscopy of patients. Among these 61 ulcers, 44 were duodenal ulcer, 22 gastric 
      ulcer (5 patients had the both duodenal and gastric ulcers). Multiple biopsies 
      were taken and be sent to laboratory for Rapid Urease Test and pathological 
      examination. About 65.53% of patients had ulcers associated with H.pylori, 9.83% 
      had peptic ulcer disease associated with NSAIDs and 11.47% of patients had ulcers 
      associated with both H.pylori and consumption of NSAIDs. 13.11% of patients had 
      non-NSAIDs non- H.pylori peptic ulcer disease. CONCLUSION: The results of this 
      study supports the results of other studies that suggest the incidence of 
      H.pylori infection related with duodenal ulcer is common, and that non-H pylori 
      and non-NSAIDs duodenal ulcer is also common.
FAU - Rajabalinia, Hasan
AU  - Rajabalinia H
AD  - Taleghani Hospital, Internal Medicine Department, Shahid Beheshti University of 
      Medical Sciences, Tehran, Iran.
FAU - Ghobakhlou, Mehdi
AU  - Ghobakhlou M
AD  - Taleghani Hospital, Internal Medicine Department, Shahid Beheshti University of 
      Medical Sciences, Tehran, Iran.
FAU - Nikpour, Shahriar
AU  - Nikpour S
AD  - Loghman Hakim Hospital, Internal Medicine Department, Shahid Beheshti University 
      of Medical Sciences, Tehran, Iran.
FAU - Dabiri, Reza
AU  - Dabiri R
AD  - Taleghani Hospital, Internal Medicine Department, Shahid Beheshti University of 
      Medical Sciences, Tehran, Iran.
FAU - Bahriny, Rasoul
AU  - Bahriny R
AD  - Taleghani Hospital, Internal Medicine Department, Shahid Beheshti University of 
      Medical Sciences, Tehran, Iran.
FAU - Sherafat, Somayeh Jahani
AU  - Sherafat SJ
AD  - Taleghani Hospital, Internal Medicine Department, Shahid Beheshti University of 
      Medical Sciences, Tehran, Iran.
FAU - Moghaddam, Pardis Ketabi
AU  - Moghaddam PK
AD  - Taleghani Hospital, Internal Medicine Department, Shahid Beheshti University of 
      Medical Sciences, Tehran, Iran.
FAU - Alizadeh, Amirhoushang Mohammad
AU  - Alizadeh AM
AD  - Taleghani Hospital, Internal Medicine Department, Shahid Beheshti University of 
      Medical Sciences, Tehran, Iran.
LA  - eng
PT  - Journal Article
PL  - Iran
TA  - Gastroenterol Hepatol Bed Bench
JT  - Gastroenterology and hepatology from bed to bench
JID - 101525875
PMC - PMC4017462
OTO - NOTNLM
OT  - H.pylori
OT  - Nonsteroidal antiflammatory drugs (NSAIDs)
OT  - Peptic ulcer
OT  - Upper gastrointestinal bleeding
EDAT- 2012/10/01 00:00
MHDA- 2012/10/01 00:01
PMCR- 2012/09/01
CRDT- 2014/05/17 06:00
PHST- 2012/06/16 00:00 [received]
PHST- 2012/08/06 00:00 [accepted]
PHST- 2014/05/17 06:00 [entrez]
PHST- 2012/10/01 00:00 [pubmed]
PHST- 2012/10/01 00:01 [medline]
PHST- 2012/09/01 00:00 [pmc-release]
AID - GHFBB-5-190 [pii]
PST - ppublish
SO  - Gastroenterol Hepatol Bed Bench. 2012 Fall;5(4):190-6.