PMID- 24837707 OWN - NLM STAT- MEDLINE DCOM- 20150821 LR - 20221207 IS - 1347-4820 (Electronic) IS - 1346-9843 (Linking) VI - 78 IP - 7 DP - 2014 TI - Safety of exercise-based cardiac rehabilitation and exercise testing for cardiac patients in Japan: a nationwide survey. PG - 1646-53 AB - BACKGROUND: The safety of exercise-based cardiac rehabilitation (CR) has not been investigated in Japan, so a nationwide survey was conducted to investigate the incidence of adverse events (AEs) associated with CR and exercise testing. METHODS AND RESULTS: In total, 136 hospitals reported operating recovery-phase CR programs, amounting to 383,096 patient-hours of exercise training. The incidence rates of all AEs and life-threatening AEs (LAE: death, cardiac arrest, acute myocardial infarction, cardiac rupture) during exercise sessions were 12 and 1 event/383,096 patient-hours (3.13 and 0.26 events/100,000patient-hours), respectively. When CR programs were categorized as "Formal" in which an exercise prescription based on exercise testing was issued to individual patients or "Non-formal" without exercise prescription, the incidence of AEs during and within the 24 h after an exercise session was significantly lower in the Formal than the Non-formal CR programs (P<0.001), despite similar hospital size and coronary intervention volumes between the 2 category hospitals. Moreover, LAEs did not occur in 277,721 patient-hours in Formal CR, whereas 2 LAEs occurred in 105,375 patient-hours in Non-formal CR (P<0.05). During 469,215 exercise testing sessions, 3 LAEs (0.64 event/100,000tests) and 31 non-LAEs (6.61 events/100,000tests) occurred. CONCLUSIONS: This first nationwide survey in Japan revealed that both exercise-based CR and exercise testing are generally safe, and that Formal CR, in which an individual exercise prescription is determined by exercise testing, is particularly safe. FAU - Saito, Masahiko AU - Saito M AD - Cardiology, Morioka Red Cross Hospital. FAU - Ueshima, Kenji AU - Ueshima K FAU - Saito, Muneyasu AU - Saito M FAU - Iwasaka, Toshiji AU - Iwasaka T FAU - Daida, Hiroyuki AU - Daida H FAU - Kohzuki, Masahiro AU - Kohzuki M FAU - Makita, Shigeru AU - Makita S FAU - Adachi, Hitoshi AU - Adachi H FAU - Yokoi, Hiroyoshi AU - Yokoi H FAU - Omiya, Kazuto AU - Omiya K FAU - Mikouchi, Hiroshi AU - Mikouchi H FAU - Yokoyama, Hiroyuki AU - Yokoyama H FAU - Goto, Yoichi AU - Goto Y CN - Japanese Cardiac Rehabilitation Survey Investigators LA - eng PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't DEP - 20140519 PL - Japan TA - Circ J JT - Circulation journal : official journal of the Japanese Circulation Society JID - 101137683 SB - IM CIN - Circ J. 2014;78(7):1569-70. PMID: 24899530 MH - Asian People MH - Disease-Free Survival MH - Exercise Therapy/adverse effects/*methods MH - Female MH - Health Care Surveys MH - Heart Diseases/*mortality/*rehabilitation MH - Humans MH - Japan/epidemiology MH - Male MH - Survival Rate EDAT- 2014/05/20 06:00 MHDA- 2015/08/22 06:00 CRDT- 2014/05/20 06:00 PHST- 2014/05/20 06:00 [entrez] PHST- 2014/05/20 06:00 [pubmed] PHST- 2015/08/22 06:00 [medline] AID - DN/JST.JSTAGE/circj/CJ-13-1590 [pii] AID - 10.1253/circj.cj-13-1590 [doi] PST - ppublish SO - Circ J. 2014;78(7):1646-53. doi: 10.1253/circj.cj-13-1590. Epub 2014 May 19.