PMID- 24837929
OWN - NLM
STAT- MEDLINE
DCOM- 20151104
LR  - 20181202
IS  - 1873-7072 (Electronic)
IS  - 0308-8146 (Linking)
VI  - 161
DP  - 2014 Oct 15
TI  - Optimisation of ultrasound-assisted reverse micelles dispersive liquid-liquid 
      micro-extraction by Box-Behnken design for determination of acetoin in butter 
      followed by high performance liquid chromatography.
PG  - 120-6
LID - S0308-8146(14)00434-8 [pii]
LID - 10.1016/j.foodchem.2014.03.043 [doi]
AB  - A novel approach, ultrasound-assisted reverse micelles dispersive liquid-liquid 
      microextraction (USA-RM-DLLME) followed by high performance liquid chromatography 
      (HPLC) was developed for selective determination of acetoin in butter. The melted 
      butter sample was diluted and homogenised by n-hexane and Triton X-100, 
      respectively. Subsequently, 400muL of distilled water was added and the 
      microextraction was accelerated by 4min sonication. After 8.5min of 
      centrifugation, sedimented phase (surfactant-rich phase) was withdrawn by 
      microsyringe and injected into the HPLC system for analysis. The influence of 
      effective variables was optimised using Box-Behnken design (BBD) combined with 
      desirability function (DF). Under optimised experimental conditions, the 
      calibration graph was linear over the range of 0.6-200mgL(-1). The detection 
      limit of method was 0.2mgL(-1) and coefficient of determination was 0.9992. The 
      relative standard deviations (RSDs) were less than 5% (n=5) while the recoveries 
      were in the range of 93.9-107.8%.
CI  - Copyright (c) 2014. Published by Elsevier Ltd.
FAU - Roosta, Mostafa
AU  - Roosta M
AD  - Chemistry Department, Yasouj University, Yasouj 75918-74831, Iran.
FAU - Ghaedi, Mehrorang
AU  - Ghaedi M
AD  - Chemistry Department, Yasouj University, Yasouj 75918-74831, Iran. Electronic 
      address: m_ghaedi@mail.yu.ac.ir.
FAU - Daneshfar, Ali
AU  - Daneshfar A
AD  - Department of Chemistry, University of Ilam, P.O. Box 65315-516, Ilam, Iran. 
      Electronic address: adaneshfar@yahoo.com.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140404
PL  - England
TA  - Food Chem
JT  - Food chemistry
JID - 7702639
RN  - 0 (Micelles)
RN  - 8029-34-3 (Butter)
RN  - BG4D34CO2H (Acetoin)
SB  - IM
MH  - Acetoin/*chemistry
MH  - Butter/*analysis
MH  - Chromatography, High Pressure Liquid/*methods
MH  - Liquid Phase Microextraction/*methods
MH  - Micelles
MH  - Ultrasonics
OTO - NOTNLM
OT  - Acetoin
OT  - Box-Behnken design
OT  - Desirability function
OT  - Response surface methodology
OT  - Ultrasound-assisted reverse micelles dispersive liquid-liquid microextraction
EDAT- 2014/05/20 06:00
MHDA- 2015/11/05 06:00
CRDT- 2014/05/20 06:00
PHST- 2012/11/05 00:00 [received]
PHST- 2014/03/04 00:00 [revised]
PHST- 2014/03/09 00:00 [accepted]
PHST- 2014/05/20 06:00 [entrez]
PHST- 2014/05/20 06:00 [pubmed]
PHST- 2015/11/05 06:00 [medline]
AID - S0308-8146(14)00434-8 [pii]
AID - 10.1016/j.foodchem.2014.03.043 [doi]
PST - ppublish
SO  - Food Chem. 2014 Oct 15;161:120-6. doi: 10.1016/j.foodchem.2014.03.043. Epub 2014 
      Apr 4.