PMID- 24839544
OWN - PIP
STAT- PubMed-not-MEDLINE
DCOM- 20140519
LR  - 20211021
IS  - 0368-0762 (Print)
IS  - 2046-0481 (Electronic)
IS  - 0368-0762 (Linking)
VI  - 67
IP  - 1
DP  - 2014
TI  - Phylogenetic comparison of porcine circovirus type 2 (PCV2) and porcine 
      reproductive respiratory syndrome virus (PRRSV) strains detected in domestic pigs 
      until 2008 and in 2012 in Croatia.
PG  - 9
LID - 10.1186/2046-0481-67-9 [doi]
AB  - BACKGROUND: Porcine circovirus type 2 (PCV2) and porcine reproductive and 
      respiratory syndrome virus (PRRSV) have been present for the last 2 decades in 
      Croatia, causing large economical losses in the pig production. The clinical 
      features of the infections are mostly manifested by the development of 
      respiratory problems, weight loss and poor growth performance, as well as 
      reproductive failure in pregnant sows. Even though the infections are 
      continuously recognized in some regions in Croatia, the heterogeneity of the 
      detected viral strains from 2012 has not yet been investigated. The objective of 
      this study was to compare virus strains of PCV2 and PRRSV detected until 2008 in 
      Croatia with strains isolated in 2012 to gain a better epidemiological 
      understanding of these two infections. RESULTS: PCV2 and PRRSV strains detected 
      in 2012 in fattening pigs from regions where these two diseases have been 
      previously described were compared to strains that have been detected in the same 
      regions within the past two decades. The phylogenetic analysis revealed that the 
      circulating PCV2 and PRRSV strains are distantly related to the previously 
      described Croatian viral strains. However, when compared to known isolates from 
      the GenBank a high genetic identity of PRRSV isolates with isolates from Hungary, 
      Denmark and the Netherlands was found. CONCLUSION: The results of this study 
      reveal that even though PCV2 and PRRSV are constantly present in the investigated 
      regions in Croatia, the viral strains found in 2012 genetically differ from those 
      detected in earlier years. This indicates that new entries into the pig 
      population appeared with regard to both infections, probably as a result of pig 
      trade.
FAU - Prpic, Jelena
AU  - Prpic J
AD  - Croatian Veterinary Institute, Savska cesta 143, Zagreb, Croatia.
FAU - Keros, Tomislav
AU  - Keros T
AD  - Croatian Veterinary Institute, Savska cesta 143, Zagreb, Croatia.
FAU - Bedekovic, Tomislav
AU  - Bedekovic T
AD  - Croatian Veterinary Institute, Savska cesta 143, Zagreb, Croatia.
FAU - Brnic, Dragan
AU  - Brnic D
AD  - Croatian Veterinary Institute, Savska cesta 143, Zagreb, Croatia.
FAU - Cvetnic, Zeljko
AU  - Cvetnic Z
AD  - Croatian Veterinary Institute, Savska cesta 143, Zagreb, Croatia.
FAU - Roic, Besi
AU  - Roic B
AD  - Croatian Veterinary Institute, Savska cesta 143, Zagreb, Croatia.
FAU - Jemersic, Lorena
AU  - Jemersic L
AD  - Croatian Veterinary Institute, Savska cesta 143, Zagreb, Croatia.
LA  - eng
PT  - Journal Article
DEP - 20140514
PL  - Ireland
TA  - Ir Vet J
JT  - Irish veterinary journal
JID - 0100762
PMC - PMC4024209
OTO - NOTNLM
OT  - Croatia
OT  - Genetic diversity
OT  - PCV2
OT  - PRRSV
EDAT- 2014/05/20 06:00
MHDA- 2014/05/20 06:01
PMCR- 2014/05/14
CRDT- 2014/05/20 06:00
PHST- 2013/10/02 00:00 [received]
PHST- 2014/04/28 00:00 [accepted]
PHST- 2014/05/20 06:00 [entrez]
PHST- 2014/05/20 06:00 [pubmed]
PHST- 2014/05/20 06:01 [medline]
PHST- 2014/05/14 00:00 [pmc-release]
AID - 2046-0481-67-9 [pii]
AID - 10.1186/2046-0481-67-9 [doi]
PST - epublish
SO  - Ir Vet J. 2014 May 14;67(1):9. doi: 10.1186/2046-0481-67-9. eCollection 2014.