PMID- 24841920
OWN - NLM
STAT- MEDLINE
DCOM- 20150821
LR  - 20181202
IS  - 1537-4505 (Electronic)
IS  - 1531-7129 (Linking)
VI  - 35
IP  - 7
DP  - 2014 Aug
TI  - Surgical outcomes in cystic vestibular schwannoma versus solid vestibular 
      schwannoma.
PG  - 1266-70
LID - 10.1097/MAO.0000000000000435 [doi]
AB  - OBJECTIVE: To review the postoperative surgical outcomes of cystic vestibular 
      schwannomas (CVSs), especially facial nerve outcomes, and compare these results 
      with those from matched solid vestibular schwannomas (SVS) resected during the 
      same period at a tertiary referral center. STUDY DESIGN: Retrospective case 
      series. METHODS: One hundred thirty-one surgically managed patients with cystic 
      vestibular schwannomas (CVSs) were age, sex, and tumor size matched to 131 
      surgically managed patients with solid vestibular schwannomas (SVSs). 
      Demographics, tumor morphology, surgical approach, extent of resection, facial 
      and nonfacial complications, and recurrence rates were compared between the 2 
      groups. Subtotal removal was defined as removal of at least 95% of the tumor. 
      RESULTS: The mean maximal tumor diameter was 2.8 cm for both groups. For CVS, 
      gross total tumor resection (GTR) was achieved in 92 patients (70.2%), and 
      subtotal tumor resection (STR) was achieved in 39 patients (29.8%). Postoperative 
      facial nerve outcomes at 1-year follow-up were good (HB Grade I-III) in 116 
      (88.5%) of 131 CVS patients. Twenty-three patients developed nonfacial 
      nerve-related complications (17.6%). For SVS, GTR was achieved in 102 patients 
      (77.9%), and STR was achieved in 29 patients (22.1%). Postoperative facial nerve 
      outcomes at 1-year follow-up were good (HB Grade I-III) in 118 (90.1%) of 131 SVS 
      patients. Nonfacial nerve related complications occurred in 14 patients (10.7%). 
      None of the differences in outcome between the 2 groups were statistically 
      significant. CONCLUSION: The difference in surgical outcomes is minimal between 
      patients with CVS and those with SVS, not reaching statistical significance. We 
      think, with judicious surgical management, similar outcomes can be achieved in 
      cystic tumors and solid tumors.
FAU - Tang, Ing Ping
AU  - Tang IP
AD  - *Department of ORL-HNS, daggerDepartment of Neurosurgery, Salford Royal Hospital, 
      Manchester, U.K.; double daggerDepartment of ORL-HNS, University Malaysia Sarawak, Malaysia; 
       section signSchool of Cancer and Enabling Services, University of Manchester; and 
       parallelManchester Ear Nose and Throat Clinic, Manchester, U.K.
FAU - Freeman, Simon R
AU  - Freeman SR
FAU - Rutherford, Scott A
AU  - Rutherford SA
FAU - King, Andrew T
AU  - King AT
FAU - Ramsden, Richard T
AU  - Ramsden RT
FAU - Lloyd, Simon K W
AU  - Lloyd SK
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - Otol Neurotol
JT  - Otology & neurotology : official publication of the American Otological Society, 
      American Neurotology Society [and] European Academy of Otology and Neurotology
JID - 100961504
SB  - IM
MH  - Facial Nerve Injuries/*etiology
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Male
MH  - Neoplasm Recurrence, Local/*pathology
MH  - Neuroma, Acoustic/pathology/*surgery
MH  - Otologic Surgical Procedures/*adverse effects
MH  - Postoperative Period
MH  - Retrospective Studies
MH  - Treatment Outcome
EDAT- 2014/05/21 06:00
MHDA- 2015/08/22 06:00
CRDT- 2014/05/21 06:00
PHST- 2014/05/21 06:00 [entrez]
PHST- 2014/05/21 06:00 [pubmed]
PHST- 2015/08/22 06:00 [medline]
AID - 10.1097/MAO.0000000000000435 [doi]
PST - ppublish
SO  - Otol Neurotol. 2014 Aug;35(7):1266-70. doi: 10.1097/MAO.0000000000000435.