PMID- 24841951
OWN - NLM
STAT- MEDLINE
DCOM- 20151006
LR  - 20221207
IS  - 1708-0428 (Electronic)
IS  - 0960-8923 (Linking)
VI  - 24
IP  - 11
DP  - 2014 Nov
TI  - Impact of different criteria on type 2 diabetes remission rate after bariatric 
      surgery.
PG  - 1881-7
LID - 10.1007/s11695-014-1282-2 [doi]
AB  - BACKGROUND: Laparoscopic sleeve gastrectomy (LSG) and laparoscopic Roux-en-Y 
      gastric bypass (LRYGB) achieve similar type 2 diabetes mellitus (T2DM) remission 
      rates. Since a great variability exists in defining T2DM remission, an expert 
      panel proposed partial and complete remission criteria that include the 
      maintenance of fasting plasma glucose (FPG) and glycosylated hemoglobin (A1c) 
      objectives for at least 1 year. The 2-year T2DM remission rate and time needed to 
      reach it after LSG or LRYGB were compared using different remission criteria. 
      METHODS: This was a prospective cohort study of 55 T2DM subjects operated on with 
      LSG (n = 21) or LRYGB (n = 34). Four models for defining remission were used: 
      Buchwald criteria (FPG <100 mg/dl or A1c <6 %), American Diabetes Association 
      (ADA) complete (FPG <100 mg/dl plus A1c <6 % maintained for at least 1 year), ADA 
      partial (FPG <125 mg/dl with A1c <6.5 % maintained for at least 1 year), and ADA 
      complete without time requirement. RESULTS: Both groups were comparable, except 
      for higher A1c levels in the LSG group. The remission rate ranged from 43.6 % 
      using ADA complete remission to 92.7 % with Buchwald criteria, with no 
      differences between surgical procedures. Differences were found in the time to 
      achieve remission only when ADA complete remission criteria (5.1 +/- 2.9 months 
      LRYGB and 9.0 +/- 3.8 months LSG, p = 0.014) and ADA without time requirement 
      criteria (4.9 +/- 2.7 months LRYGB and 8.4 +/- 3.9 months LSG, p = 0.005) were used. 
      CONCLUSIONS: T2DM remission rate varies widely depending on the criteria used for 
      its definition. Remission occurred sooner after LRYGB when the strictest criteria 
      to define remission were used.
FAU - Mas-Lorenzo, A
AU  - Mas-Lorenzo A
AD  - Department of Endocrinology and Nutrition, Hospital del Mar, Passeig Maritim, 
      25-29, 08003, Barcelona, Spain.
FAU - Benaiges, D
AU  - Benaiges D
FAU - Flores-Le-Roux, J A
AU  - Flores-Le-Roux JA
FAU - Pedro-Botet, J
AU  - Pedro-Botet J
FAU - Ramon, J M
AU  - Ramon JM
FAU - Parri, A
AU  - Parri A
FAU - Villatoro, M
AU  - Villatoro M
FAU - Chillaron, J
AU  - Chillaron J
FAU - Pera, M
AU  - Pera M
FAU - Grande, L
AU  - Grande L
FAU - Goday, A
AU  - Goday A
CN  - Obemar Group
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Obes Surg
JT  - Obesity surgery
JID - 9106714
RN  - 0 (Glycated Hemoglobin A)
RN  - Diabetes Mellitus, Noninsulin-Dependent, 2
SB  - IM
MH  - Bariatric Surgery/*methods
MH  - Cohort Studies
MH  - Diabetes Mellitus, Type 2/blood/complications/*therapy
MH  - Female
MH  - Gastrectomy/methods
MH  - Gastric Bypass/methods
MH  - Glycated Hemoglobin/metabolism
MH  - Humans
MH  - Laparoscopy/methods
MH  - Male
MH  - Middle Aged
MH  - Obesity, Morbid/complications/*surgery
MH  - *Patient Selection
MH  - Prospective Studies
MH  - Remission Induction
MH  - Treatment Outcome
EDAT- 2014/05/21 06:00
MHDA- 2015/10/07 06:00
CRDT- 2014/05/21 06:00
PHST- 2014/05/21 06:00 [entrez]
PHST- 2014/05/21 06:00 [pubmed]
PHST- 2015/10/07 06:00 [medline]
AID - 10.1007/s11695-014-1282-2 [doi]
PST - ppublish
SO  - Obes Surg. 2014 Nov;24(11):1881-7. doi: 10.1007/s11695-014-1282-2.