PMID- 24842231 OWN - NLM STAT- MEDLINE DCOM- 20150615 LR - 20150112 IS - 1876-4738 (Electronic) IS - 0914-5087 (Linking) VI - 65 IP - 1 DP - 2015 Jan TI - Exploring the blood volume amplitude and pulse transit time during anger recall in patients with coronary artery disease. PG - 50-6 LID - S0914-5087(14)00107-5 [pii] LID - 10.1016/j.jjcc.2014.03.012 [doi] AB - BACKGROUND AND PURPOSE: One psychopathological mechanism that links anger to coronary artery disease (CAD) is cardiac autonomic imbalance. Blood volume amplitude (BVA) and pulse transit time (PTT) are related to peripheral arterial elasticity and cardiac conduction, which are used as indirect markers for autonomic activation. The purposes of this study were to examine the relationships between BVA and PTT, and the reactivity of BVA and PTT during the anger recall task in patients with CAD. METHODS AND SUBJECTS: A total of 112 patients with CAD and 93 healthy controls were recruited; BVA and PTT were collected during baseline, the neutral episode, the anger episode, and after recovery. RESULTS: There were significant positive correlations between BVA and PTT in all participants. BVA reactivity during the anger episode was greater in patients with CAD than in healthy controls, and there were also lower BVA recovery values after the neutral and anger episodes. However, there was no significant difference in BVA reactivity between the two groups in the neutral episode. PTT recovered to baseline levels after the neutral and anger episodes in healthy controls, but not in the patients with CAD. CONCLUSION: BVA and PTT were associated with peripheral vascular elasticity and cardiac conduction that were regulated by the cardiac autonomic system. Peripheral vasoconstriction and changes in travel time between left ventricular and peripheral vasculature during the anger episode, and impaired recovery to baseline levels may relate to the psychopathological mechanisms of CAD. CI - Copyright (c) 2014 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved. FAU - Lin, I-Mei AU - Lin IM AD - Department of Psychology, Kaohsiung Medical University, Kaohsiung 807, Taiwan. Electronic address: psyiml@kmu.edu.tw. FAU - Fan, Sheng-Yu AU - Fan SY AD - Institute of Gerontology, National Cheng Kung University, Tainan 701, Taiwan. FAU - Lu, Ye-Hsu AU - Lu YH AD - Division of Cardiology, Kaohsiung Medical University Hospital, 807, Taiwan. FAU - Lee, Chee-Siong AU - Lee CS AD - Division of Cardiology, Kaohsiung Medical University Hospital, 807, Taiwan. FAU - Wu, Kuan-Ta AU - Wu KT AD - Department of Preventive Medicine, Kaohsiung Medical University Hospital, 807, Taiwan. FAU - Ji, Hui-Jing AU - Ji HJ AD - Department of Psychology, Kaohsiung Medical University, Kaohsiung 807, Taiwan. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20140517 PL - Netherlands TA - J Cardiol JT - Journal of cardiology JID - 8804703 SB - IM MH - Aged MH - Anger/*physiology MH - Autonomic Nervous System/physiopathology MH - Blood Vessels/physiopathology MH - *Blood Volume MH - Coronary Artery Disease/*physiopathology/*psychology MH - Elasticity MH - Female MH - Heart/innervation MH - Heart Conduction System/physiopathology MH - Humans MH - Male MH - Mental Recall/*physiology MH - Middle Aged MH - *Pulse Wave Analysis OTO - NOTNLM OT - Anger recall OT - Blood volume amplitude OT - Coronary artery disease OT - Pulse transit time EDAT- 2014/05/21 06:00 MHDA- 2015/06/16 06:00 CRDT- 2014/05/21 06:00 PHST- 2013/10/08 00:00 [received] PHST- 2014/02/20 00:00 [revised] PHST- 2014/03/18 00:00 [accepted] PHST- 2014/05/21 06:00 [entrez] PHST- 2014/05/21 06:00 [pubmed] PHST- 2015/06/16 06:00 [medline] AID - S0914-5087(14)00107-5 [pii] AID - 10.1016/j.jjcc.2014.03.012 [doi] PST - ppublish SO - J Cardiol. 2015 Jan;65(1):50-6. doi: 10.1016/j.jjcc.2014.03.012. Epub 2014 May 17.