PMID- 24842868
OWN - NLM
STAT- MEDLINE
DCOM- 20150219
LR  - 20140923
IS  - 0003-4894 (Print)
IS  - 0003-4894 (Linking)
VI  - 123
IP  - 10
DP  - 2014 Oct
TI  - Gastroesophageal reflux in chronic cough and cough syncope and the effect of 
      antireflux treatment: case report and literature review.
PG  - 719-25
LID - 10.1177/0003489414534011 [doi]
AB  - OBJECTIVE: This study aimed to evaluate the efficacy of antireflux treatment on 
      gastroesophageal reflux (GER)-related cough syncope. METHODS: The method used was 
      a retrospective review of the outcomes of antireflux treatment with proton pump 
      inhibitor (PPI), Stretta radiofrequency (SRF), or laparoscopic fundoplication 
      (LF) of 8 patients with chronic cough and cough syncope that was clinically 
      evaluated to be GER related over a period of 2 to 5 years. RESULTS: In the 8 
      selected cases, the typical GER symptoms disappeared in 7 cases and were 
      significantly eased in 1 case. The chronic cough diminished to mild and 
      occasional occurrence in 6 cases and was completely relieved in 2 cases. 
      Meanwhile, the cough syncope disappeared in all cases. Seven of the patients 
      resumed physical and social functions after the antireflux treatments, except for 
      1 person, who had a stroke due to other causes. CONCLUSION: For chronic cough and 
      cough syncope of unknown cause, the GER assessment could be valuable. In treating 
      well-selected GER-related chronic cough and cough syncope, PPI, SRF, and LF can 
      be considered. Moreover, satisfactory restoration of physical and social 
      functions could be achieved after effective antireflux therapy.
CI  - (c) The Author(s) 2014.
FAU - Hu, Zhi-Wei
AU  - Hu ZW
AD  - Center for GER, the Second Artillery General Hospital, Beijing Normal University, 
      Beijing, China Xuanwu Hospital, Capital Medical University, Beijing, China.
FAU - Wang, Zhong-Gao
AU  - Wang ZG
AD  - Center for GER, the Second Artillery General Hospital, Beijing Normal University, 
      Beijing, China Xuanwu Hospital, Capital Medical University, Beijing, China 
      zhonggaowang@126.com.
FAU - Zhang, Yu
AU  - Zhang Y
AD  - Xuanwu Hospital, Capital Medical University, Beijing, China.
FAU - Tian, Shu-Rui
AU  - Tian SR
AD  - Xuanwu Hospital, Capital Medical University, Beijing, China.
FAU - Wu, Ji-Min
AU  - Wu JM
AD  - Xuanwu Hospital, Capital Medical University, Beijing, China.
FAU - Zhu, Guang-Chang
AU  - Zhu GC
AD  - Center for GER, the Second Artillery General Hospital, Beijing Normal University, 
      Beijing, China.
FAU - Liang, Wei-Tao
AU  - Liang WT
AD  - Center for GER, the Second Artillery General Hospital, Beijing Normal University, 
      Beijing, China.
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Review
DEP - 20140519
PL  - United States
TA  - Ann Otol Rhinol Laryngol
JT  - The Annals of otology, rhinology, and laryngology
JID - 0407300
RN  - 0 (Proton Pump Inhibitors)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Chronic Disease
MH  - Cough/etiology/*therapy
MH  - Female
MH  - Fundoplication
MH  - Gastroesophageal Reflux/*complications/*therapy
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Proton Pump Inhibitors/therapeutic use
MH  - Retrospective Studies
MH  - Syncope/etiology/*therapy
MH  - Treatment Outcome
OTO - NOTNLM
OT  - antireflux
OT  - chronic cough
OT  - cough syncope
OT  - gastroesophageal reflux
EDAT- 2014/05/21 06:00
MHDA- 2015/02/20 06:00
CRDT- 2014/05/21 06:00
PHST- 2014/05/21 06:00 [entrez]
PHST- 2014/05/21 06:00 [pubmed]
PHST- 2015/02/20 06:00 [medline]
AID - 0003489414534011 [pii]
AID - 10.1177/0003489414534011 [doi]
PST - ppublish
SO  - Ann Otol Rhinol Laryngol. 2014 Oct;123(10):719-25. doi: 10.1177/0003489414534011. 
      Epub 2014 May 19.