PMID- 24845547
OWN - NLM
STAT- MEDLINE
DCOM- 20150219
LR  - 20181202
IS  - 1536-0539 (Electronic)
IS  - 1536-0288 (Linking)
VI  - 28
IP  - 2
DP  - 2014 Jun
TI  - Disrupting the downward spiral of chronic pain and opioid addiction with 
      mindfulness-oriented recovery enhancement: a review of clinical outcomes and 
      neurocognitive targets.
PG  - 122-9
LID - 10.3109/15360288.2014.911791 [doi]
AB  - Prescription opioid misuse and addiction among chronic pain patients are problems 
      of growing medical and social significance. Chronic pain patients often require 
      intervention to improve their well-being and functioning, and yet, the most 
      commonly available form of pharmacotherapy for chronic pain is centered on opioid 
      analgesics--drugs that have high abuse liability. Consequently, health care and 
      legal systems are often stymied in their attempts to intervene with individuals 
      who suffer from both pain and addiction. As such, novel, nonpharmacologic 
      interventions are needed to complement pharmacotherapy and interrupt the cycle of 
      behavioral escalation. The purpose of this paper is to describe how the downward 
      spiral of chronic pain and prescription opioid misuse may be targeted by one such 
      intervention, Mindfulness-Oriented Recovery Enhancement (MORE), a new behavioral 
      treatment that integrates elements from mindfulness training, 
      cognitive-behavioral therapy, and positive psychology. The clinical outcomes and 
      neurocognitive mechanisms of this intervention are reviewed with respect to their 
      effects on the risk chain linking chronic pain and prescription opioid misuse. 
      Future directions for clinical and pharmacologic research are discussed.
FAU - Garland, Eric L
AU  - Garland EL
LA  - eng
GR  - R34DA037005/DA/NIDA NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Review
DEP - 20140520
PL  - England
TA  - J Pain Palliat Care Pharmacother
JT  - Journal of pain & palliative care pharmacotherapy
JID - 101125608
RN  - 0 (Analgesics, Opioid)
SB  - IM
MH  - Analgesics, Opioid/administration & dosage/*adverse effects
MH  - Chronic Pain/*drug therapy
MH  - Cognitive Behavioral Therapy/methods
MH  - Humans
MH  - Mindfulness/*methods
MH  - Opioid-Related Disorders/*rehabilitation
MH  - Prescription Drug Misuse/adverse effects
OTO - NOTNLM
OT  - addiction
OT  - chronic
OT  - mindfulness
OT  - misuse
OT  - neurocognitive
OT  - opioid
OT  - pain
OT  - pharmacotherapy
EDAT- 2014/05/23 06:00
MHDA- 2015/02/20 06:00
CRDT- 2014/05/22 06:00
PHST- 2014/05/22 06:00 [entrez]
PHST- 2014/05/23 06:00 [pubmed]
PHST- 2015/02/20 06:00 [medline]
AID - 10.3109/15360288.2014.911791 [doi]
PST - ppublish
SO  - J Pain Palliat Care Pharmacother. 2014 Jun;28(2):122-9. doi: 
      10.3109/15360288.2014.911791. Epub 2014 May 20.