PMID- 24854567
OWN - NLM
STAT- MEDLINE
DCOM- 20150417
LR  - 20220330
IS  - 1557-3117 (Electronic)
IS  - 1053-2498 (Linking)
VI  - 33
IP  - 8
DP  - 2014 Aug
TI  - Emotional symptoms and quality of life in patients with pulmonary arterial 
      hypertension.
PG  - 800-8
LID - S1053-2498(14)01085-7 [pii]
LID - 10.1016/j.healun.2014.04.003 [doi]
AB  - BACKGROUND: Limited evidence exists on the nature and degree of emotional 
      problems in pulmonary arterial hypertension (PAH) and their association with 
      patients' health-related quality of life (HRQOL). METHODS: This cross-sectional 
      study examined the presence of depression, anxiety, and stress symptoms, and 
      their association with disease-specific and generic HRQOL. A total of 101 
      patients (73% women) with PAH (age, 55.4 +/- 16.4 years; 42.6% in New York Heart 
      Association [NYHA] class II) completed the Depression, Anxiety, and Stress Scale, 
      the generic Medical Outcomes Study Short-Form 36-Item (SF-36) Health Survey, and 
      the disease-specific Minnesota Living With Heart Failure Questionnaire (MLHFQ) 
      HRQOL instrument. The association between emotional problems and HRQOL was 
      determined using multivariable linear regression analyses, controlling for 
      demographic and disease-related characteristics. RESULTS: Of the patients, 32.6%, 
      48%, and 27.6% experienced depressive, anxiety or stress symptoms, respectively. 
      HRQOL was >1 standard deviation below population norms for the SF-36 Physical 
      Component Summary. Depressive symptoms, NYHA class, and being disabled explained 
      46% of the total variance of the MLHFQ. Emotional problems did not contribute to 
      the SF-36 Physical Component Summary but explained part of the variance of the 
      physical sub-scales of the SF-36 role limitations due to physical problems, 
      bodily pain, and general health. CONCLUSIONS: The high presence of emotional 
      problems warrants regular screening and appropriate psychotherapeutic and/or 
      pharmacological treatment. Which strategies could improve PAH patients' HRQOL 
      remains to be investigated.
CI  - Copyright (c) 2014 International Society for Heart and Lung Transplantation. 
      Published by Elsevier Inc. All rights reserved.
FAU - M M Vanhoof, Jasper
AU  - M M Vanhoof J
AD  - Health Services and Nursing Research, Department of Public Health and Primary 
      Care.
FAU - Delcroix, Marion
AU  - Delcroix M
AD  - Respiratory Division, University Hospitals, and Department of Clinical and 
      Experimental Medicine, University of Leuven, (KU Leuven) Leuven, Belgium.
FAU - Vandevelde, Ellen
AU  - Vandevelde E
AD  - Respiratory Division, University Hospitals, and Department of Clinical and 
      Experimental Medicine, University of Leuven, (KU Leuven) Leuven, Belgium.
FAU - Denhaerynck, Kris
AU  - Denhaerynck K
AD  - TriloStatistical Consultancy, Basel, Switzerland.
FAU - Wuyts, Wim
AU  - Wuyts W
AD  - Respiratory Division, University Hospitals, and Department of Clinical and 
      Experimental Medicine, University of Leuven, (KU Leuven) Leuven, Belgium.
FAU - Belge, Catharina
AU  - Belge C
AD  - Respiratory Division, University Hospitals, and Department of Clinical and 
      Experimental Medicine, University of Leuven, (KU Leuven) Leuven, Belgium.
FAU - Dobbels, Fabienne
AU  - Dobbels F
AD  - Health Services and Nursing Research, Department of Public Health and Primary 
      Care. Electronic address: fabienne.dobbels@med.kuleuven.be.
LA  - eng
PT  - Journal Article
DEP - 20140419
PL  - United States
TA  - J Heart Lung Transplant
JT  - The Journal of heart and lung transplantation : the official publication of the 
      International Society for Heart Transplantation
JID - 9102703
SB  - IM
MH  - Adult
MH  - Aged
MH  - Anxiety/epidemiology
MH  - Cross-Sectional Studies
MH  - Depression/epidemiology
MH  - Emotions/*physiology
MH  - Female
MH  - Health Surveys
MH  - Humans
MH  - Hypertension, Pulmonary/*physiopathology/*psychology
MH  - Linear Models
MH  - Male
MH  - Middle Aged
MH  - Prevalence
MH  - Quality of Life/*psychology
MH  - Stress, Psychological/epidemiology
OTO - NOTNLM
OT  - Pulmonary arterial hypertension
OT  - mood problems
OT  - psychological functioning
OT  - quality of life
EDAT- 2014/05/24 06:00
MHDA- 2015/04/18 06:00
CRDT- 2014/05/24 06:00
PHST- 2013/09/19 00:00 [received]
PHST- 2014/03/05 00:00 [revised]
PHST- 2014/04/16 00:00 [accepted]
PHST- 2014/05/24 06:00 [entrez]
PHST- 2014/05/24 06:00 [pubmed]
PHST- 2015/04/18 06:00 [medline]
AID - S1053-2498(14)01085-7 [pii]
AID - 10.1016/j.healun.2014.04.003 [doi]
PST - ppublish
SO  - J Heart Lung Transplant. 2014 Aug;33(8):800-8. doi: 10.1016/j.healun.2014.04.003. 
      Epub 2014 Apr 19.