PMID- 24856511
OWN - NLM
STAT- MEDLINE
DCOM- 20150416
LR  - 20140526
IS  - 1873-4324 (Electronic)
IS  - 0003-2670 (Linking)
VI  - 830
DP  - 2014 Jun 9
TI  - Chiral metal-organic framework used as stationary phases for capillary 
      electrochromatography.
PG  - 49-55
LID - S0003-2670(14)00508-X [pii]
LID - 10.1016/j.aca.2014.04.054 [doi]
AB  - Metal-organic frameworks (MOFs) have received great attention as novel media in 
      separation sciences because of their fascinating structures and unusual 
      properties. However, to the best of our knowledge, there has been no attempt to 
      utilize chiral MOFs as stationary phases in capillary electrochromatography 
      (CEC). In this study, a homochiral helical MOF [Zn2(D-Cam)2(4,4'-bpy)]n 
      (D-Cam=D-(+)-camphoric acid, 4,4'-bpy=4,4'-bipyridine) was explored as the chiral 
      stationary phase in open tubular capillary electrochromatography (OT-CEC) for 
      separation of chiral compounds and isomers. The MOFs coated column has been 
      developed using a simple procedure via MOFs post-coated on the sodium silicate 
      layer. The baseline separations of flavanone and praziquantel were achieved on 
      the MOFs coated column with high resolution of more than 2.10. The influences of 
      pH, organic modifier content and buffer concentration on separation were 
      investigated. Besides, the separations of isomers (nitrophenols and ionones) were 
      evaluated. The relative standard deviations (RSDs) for the retention time of 
      run-to-run, day-to-day and column-to-column were 1.04%, 2.16% and 3.07%, 
      respectively. The results demonstrated that chiral MOFs are promising for 
      enantioseparation in CEC.
CI  - Copyright (c) 2014 Elsevier B.V. All rights reserved.
FAU - Fei, Zhi-Xin
AU  - Fei ZX
AD  - Department of Chemistry, Yunnan Normal University, Kunming 650500, PR China.
FAU - Zhang, Mei
AU  - Zhang M
AD  - Department of Chemistry, East China Normal University, Shanghai 200241, PR China.
FAU - Zhang, Jun-Hui
AU  - Zhang JH
AD  - Department of Chemistry, East China Normal University, Shanghai 200241, PR China.
FAU - Yuan, Li-Ming
AU  - Yuan LM
AD  - Department of Chemistry, Yunnan Normal University, Kunming 650500, PR China; 
      Department of Chemistry, East China Normal University, Shanghai 200241, PR China. 
      Electronic address: yuan_limingpd@aliyun.com.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140501
PL  - Netherlands
TA  - Anal Chim Acta
JT  - Analytica chimica acta
JID - 0370534
RN  - 0 (Nitrophenols)
RN  - 0 (Norisoprenoids)
RN  - 0 (Organometallic Compounds)
SB  - IM
MH  - *Capillary Electrochromatography
MH  - Molecular Structure
MH  - Nitrophenols/*isolation & purification
MH  - Norisoprenoids/*isolation & purification
MH  - Organometallic Compounds/*chemistry
OTO - NOTNLM
OT  - Chiral separation
OT  - Metal-organic framework
OT  - Open tubular capillary electrochromatography
OT  - Stationary phase
EDAT- 2014/05/27 06:00
MHDA- 2015/04/17 06:00
CRDT- 2014/05/27 06:00
PHST- 2013/12/11 00:00 [received]
PHST- 2014/04/17 00:00 [revised]
PHST- 2014/04/28 00:00 [accepted]
PHST- 2014/05/27 06:00 [entrez]
PHST- 2014/05/27 06:00 [pubmed]
PHST- 2015/04/17 06:00 [medline]
AID - S0003-2670(14)00508-X [pii]
AID - 10.1016/j.aca.2014.04.054 [doi]
PST - ppublish
SO  - Anal Chim Acta. 2014 Jun 9;830:49-55. doi: 10.1016/j.aca.2014.04.054. Epub 2014 
      May 1.