PMID- 24857688 OWN - NLM STAT- MEDLINE DCOM- 20141014 LR - 20140802 IS - 1879-1891 (Electronic) IS - 0002-9394 (Linking) VI - 158 IP - 2 DP - 2014 Aug TI - Radial versus raster spectral-domain optical coherence tomography scan patterns for detection of macular pathology. PG - 345-353.e2 LID - S0002-9394(14)00247-5 [pii] LID - 10.1016/j.ajo.2014.05.013 [doi] AB - PURPOSE: To compare the 6-line radial vs the 25-line raster spectral-domain optical coherence tomography (SD OCT) acquisition patterns at detecting intraretinal fluid, subretinal fluid, vitreomacular traction, and full-thickness macular hole (MH). DESIGN: Retrospective cross-sectional analysis. METHODS: Series of 365 eyes with neovascular age-related macular degeneration (AMD), diabetic macular edema (DME), central and branch retinal vein occlusion (CRVO/BRVO), central serous chorioretinopathy, vitreomacular traction, and full-thickness MH. Sequential 6-line radial and 25-line raster scans were evaluated for intraretinal/subretinal fluid and, when applicable, vitreomacular traction and MH. RESULTS: For neovascular AMD (133 scans), 7 25-line raster scans confirmed subretinal/intraretinal fluid not identified by the 6-line radial (P=.02). For DME (140 scans) and central serous chorioretinopathy (91 scans), 25-line raster confirmed fluid in 4 scans (P=.13) and 1 scan (P=.32), respectively, that was not observed with the 6-line radial. For CRVO (123 scans) and BRVO (126 scans), 25-line raster confirmed fluid on 2 (P=.25) and 4 scans (P=.13), respectively, that was not detected by the 6-line radial. Conversely, for focal vitreomacular traction (70 scans) and full-thickness MH (82 scans), 25-line raster missed focal traction (<1500 mum) and MH in 5 scans (P=.07) and 7 scans (P=.02), respectively, that were identified using the 6-line radial. CONCLUSIONS: The 6-line radial scan is statistically comparable to the 25-line raster at detecting fluid in DME, BRVO/CRVO, and central serous chorioretinopathy, but not neovascular AMD. Furthermore, it is superior to the 25-line raster pattern at detecting early MH formation, while demonstrating a positive trend in identifying focal vitreomacular traction. CI - Copyright (c) 2014 Elsevier Inc. All rights reserved. FAU - Rahimy, Ehsan AU - Rahimy E AD - Mid Atlantic Retina, The Retina Service of Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania. FAU - Rayess, Nadim AU - Rayess N AD - Mid Atlantic Retina, The Retina Service of Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania. FAU - Maguire, Joseph I AU - Maguire JI AD - Mid Atlantic Retina, The Retina Service of Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania. FAU - Hsu, Jason AU - Hsu J AD - Mid Atlantic Retina, The Retina Service of Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania. Electronic address: jhsu@midatlanticretina.com. LA - eng PT - Comparative Study PT - Journal Article PT - Observational Study PT - Research Support, Non-U.S. Gov't DEP - 20140520 PL - United States TA - Am J Ophthalmol JT - American journal of ophthalmology JID - 0370500 SB - IM MH - Aged MH - Central Serous Chorioretinopathy/*diagnosis MH - Cross-Sectional Studies MH - Diagnosis, Differential MH - Humans MH - Macula Lutea/*pathology MH - Macular Degeneration/*diagnosis MH - Macular Edema/*diagnosis MH - Middle Aged MH - Reproducibility of Results MH - Retinal Perforations/*diagnosis MH - Retinal Vein Occlusion/*diagnosis MH - Retrospective Studies MH - Tomography, Optical Coherence/*methods EDAT- 2014/05/27 06:00 MHDA- 2014/10/15 06:00 CRDT- 2014/05/27 06:00 PHST- 2014/03/14 00:00 [received] PHST- 2014/05/06 00:00 [revised] PHST- 2014/05/07 00:00 [accepted] PHST- 2014/05/27 06:00 [entrez] PHST- 2014/05/27 06:00 [pubmed] PHST- 2014/10/15 06:00 [medline] AID - S0002-9394(14)00247-5 [pii] AID - 10.1016/j.ajo.2014.05.013 [doi] PST - ppublish SO - Am J Ophthalmol. 2014 Aug;158(2):345-353.e2. doi: 10.1016/j.ajo.2014.05.013. Epub 2014 May 20.