PMID- 24859693
OWN - NLM
STAT- MEDLINE
DCOM- 20150709
LR  - 20211021
IS  - 1614-7499 (Electronic)
IS  - 0944-1344 (Linking)
VI  - 22
IP  - 6
DP  - 2015 Mar
TI  - Hydrophilic interaction liquid chromatography coupled with tandem mass 
      spectrometry for acidic herbicides and metabolites analysis in fresh water.
PG  - 3988-96
LID - 10.1007/s11356-014-2876-x [doi]
AB  - Theoretical papers and environmental applications of hydrophilic interaction 
      liquid chromatography (HILIC) have been published for a wide range of analytes, 
      but to our knowledge, no study focused on acidic herbicides (e.g., triketones, 
      phenoxy acids, sulfonylurea, and acidic metabolites of chloroacetanilides). 
      Matrix effects are the main obstacle to natural sample analysis by liquid 
      chromatography coupled with tandem mass spectrometry (MS) via an electrospray 
      ionization (ESI) interface. Therefore, we paid particular attention on limiting 
      interference by (i) adapting the emerging HILIC technique, which is generally 
      considered more sensitive than conventional reversed phase liquid chromatography 
      and (ii) optimizing the solid phase extraction (SPE) step using a design of 
      experiment. A rapid and reliable off line SPE-HILIC-ESI-MS/MS method was thus 
      developed for the quantification of acidic herbicides in fresh water, with limits 
      of quantifications (LOQs) ranging from 5 to 22 ng L(-1). Then, the analysis of 
      freshwater samples highlighted the robustness of the method, and the importance 
      of the chloroacetanilides metabolites among the studied analytes.
FAU - Fauvelle, Vincent
AU  - Fauvelle V
AD  - Irstea, UR EABX, 33612, Cestas Cedex, France, vincent.fauvelle@irstea.fr.
FAU - Mazzella, Nicolas
AU  - Mazzella N
FAU - Morin, Soizic
AU  - Morin S
FAU - Moreira, Sylvia
AU  - Moreira S
FAU - Delest, Brigitte
AU  - Delest B
FAU - Budzinski, Helene
AU  - Budzinski H
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140527
PL  - Germany
TA  - Environ Sci Pollut Res Int
JT  - Environmental science and pollution research international
JID - 9441769
RN  - 0 (Acids)
RN  - 0 (Herbicides)
RN  - 0 (Sulfonylurea Compounds)
RN  - 0 (Water Pollutants, Chemical)
SB  - IM
MH  - Acids/analysis
MH  - Chromatography, Liquid/*methods
MH  - Fresh Water/*chemistry
MH  - Herbicides/*analysis
MH  - Hydrophobic and Hydrophilic Interactions
MH  - Solid Phase Extraction/methods
MH  - Sulfonylurea Compounds/analysis
MH  - Tandem Mass Spectrometry/*methods
MH  - Water Pollutants, Chemical/*analysis
EDAT- 2014/05/27 06:00
MHDA- 2015/07/15 06:00
CRDT- 2014/05/27 06:00
PHST- 2014/01/10 00:00 [received]
PHST- 2014/04/02 00:00 [accepted]
PHST- 2014/05/27 06:00 [entrez]
PHST- 2014/05/27 06:00 [pubmed]
PHST- 2015/07/15 06:00 [medline]
AID - 10.1007/s11356-014-2876-x [doi]
PST - ppublish
SO  - Environ Sci Pollut Res Int. 2015 Mar;22(6):3988-96. doi: 
      10.1007/s11356-014-2876-x. Epub 2014 May 27.