PMID- 24861892
OWN - NLM
STAT- MEDLINE
DCOM- 20150825
LR  - 20141110
IS  - 1463-1326 (Electronic)
IS  - 1462-8902 (Linking)
VI  - 16
IP  - 12
DP  - 2014 Dec
TI  - Change in levels of physical activity after diagnosis of type 2 diabetes: an 
      observational analysis from the NAVIGATOR study.
PG  - 1265-8
LID - 10.1111/dom.12320 [doi]
AB  - Increased physical activity is known to be beneficial in people with type 2 
      diabetes mellitus (T2DM), but it is not known whether individuals change their 
      activity levels after T2DM diagnosis. The present Nateglinide and Valsartan in 
      Impaired Glucose Tolerance Outcomes Research (NAVIGATOR) trial, conducted in 
      participants with impaired glucose tolerance at high cardiovascular risk, 
      assessed ambulatory activity annually using research-grade pedometers. Oral 
      glucose tolerance tests were performed annually and repeated to confirm T2DM 
      diagnosis. This observational analysis used general linear models to compare step 
      counts before and after T2DM diagnosis in the 2816 participants with the 
      requisite data. Participants were relatively inactive at baseline, taking a 
      median (interquartile range) of 5488 (3258-8361) steps/day, which decreased after 
      T2DM diagnosis by a mean (s.e.) of 258 (64) steps/day (p < 0.0001); however, 
      after adjusting for background trend for activity, step count after T2DM 
      diagnosis was unchanged [mean (s.e.) of 103 (87) fewer steps/day; p = 0.23]. 
      Awareness of T2DM diagnosis had no impact on the trajectory of activity 
      established before the diagnosis.
CI  - (c) 2014 John Wiley & Sons Ltd.
FAU - Preiss, D
AU  - Preiss D
AD  - BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK.
FAU - Haffner, S M
AU  - Haffner SM
FAU - Thomas, L E
AU  - Thomas LE
FAU - Sun, J-L
AU  - Sun JL
FAU - Sattar, N
AU  - Sattar N
FAU - Yates, T
AU  - Yates T
FAU - J Davies, M
AU  - J Davies M
FAU - McMurray, J J
AU  - McMurray JJ
FAU - Holman, R R
AU  - Holman RR
FAU - Califf, R M
AU  - Califf RM
FAU - Kraus, W E
AU  - Kraus WE
LA  - eng
SI  - ClinicalTrials.gov/NCT00097786
PT  - Journal Article
PT  - Multicenter Study
PT  - Observational Study
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
DEP - 20140619
PL  - England
TA  - Diabetes Obes Metab
JT  - Diabetes, obesity & metabolism
JID - 100883645
RN  - 0 (Blood Glucose)
SB  - IM
MH  - *Actigraphy/instrumentation
MH  - Blood Glucose/metabolism
MH  - Blood Pressure
MH  - Cardiovascular Diseases/*prevention & control
MH  - Diabetes Mellitus, Type 2/diagnosis/*psychology/therapy
MH  - Diabetic Angiopathies/*prevention & control
MH  - Disease Progression
MH  - Exercise
MH  - Female
MH  - Glucose Tolerance Test
MH  - Health Knowledge, Attitudes, Practice
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Monitoring, Ambulatory/instrumentation
MH  - *Motor Activity
MH  - Patient Compliance
MH  - Patient Education as Topic
MH  - Risk Factors
MH  - *Risk Reduction Behavior
MH  - *Walking
OTO - NOTNLM
OT  - observational study
EDAT- 2014/05/28 06:00
MHDA- 2015/08/26 06:00
CRDT- 2014/05/28 06:00
PHST- 2013/12/19 00:00 [received]
PHST- 2014/04/18 00:00 [revised]
PHST- 2014/05/20 00:00 [accepted]
PHST- 2014/05/28 06:00 [entrez]
PHST- 2014/05/28 06:00 [pubmed]
PHST- 2015/08/26 06:00 [medline]
AID - 10.1111/dom.12320 [doi]
PST - ppublish
SO  - Diabetes Obes Metab. 2014 Dec;16(12):1265-8. doi: 10.1111/dom.12320. Epub 2014 
      Jun 19.