PMID- 24863241 OWN - NLM STAT- MEDLINE DCOM- 20150115 LR - 20140527 IS - 1873-0191 (Electronic) IS - 0928-4931 (Linking) VI - 39 DP - 2014 Jun 1 TI - Application of glass particles doped by Zn(+2) as an antimicrobial and atoxic compound in LLDPE and HDPE. PG - 403-10 LID - S0928-4931(14)00132-5 [pii] LID - 10.1016/j.msec.2014.03.015 [doi] AB - This study demonstrates the potential application of glass particles doped with Zn(+2) (GZn) as an atoxic, antimicrobial additive when used in conjunction with high density polyethylene (HDPE) and linear low density polyethylene (LLDPE) polymers. Toxicity tests demonstrated that these modified glass particles were nontoxic to human cells, and atomic absorption analyses demonstrated the migration of ionic species in quantities less than 2.0ppm for both the HDPE/GZn and LLDPE/GZn compounds. Microbiological tests demonstrated the antimicrobial effect of the pure GZn compound as well as the polymeric HDPE/GZn and LLDPE/GZn compounds. In addition, at percentages of GZn higher than 2.00wt.% and at a time of 4h, the bactericidal performance is excellent and equal for both polymeric compounds. CI - Copyright (c) 2014 Elsevier B.V. All rights reserved. FAU - Santos, M F AU - Santos MF AD - Post-Graduate Program in Science and Materials Engineering, Universidade do Extremo Sul Catarianese/UNESC, Av. Universitaria, 1105, CEP 88806-000, Criciuma, Santa Catarina, Brazil. FAU - Machado, C AU - Machado C AD - Laboratory of Advanced Materials and Processes, Universidade do Extremo Sul Catarianese/UNESC, iParque, Rod. Gov. Jorge Lacerda, km 4,5, CEP 88806-000, Criciuma, SC, Brazil. FAU - Tachinski, C G AU - Tachinski CG AD - Laboratory of Advanced Materials and Processes, Universidade do Extremo Sul Catarianese/UNESC, iParque, Rod. Gov. Jorge Lacerda, km 4,5, CEP 88806-000, Criciuma, SC, Brazil. FAU - Junior, J F AU - Junior JF AD - Laboratory of Advanced Materials and Processes, Universidade do Extremo Sul Catarianese/UNESC, iParque, Rod. Gov. Jorge Lacerda, km 4,5, CEP 88806-000, Criciuma, SC, Brazil. FAU - Piletti, R AU - Piletti R AD - Laboratory of Advanced Materials and Processes, Universidade do Extremo Sul Catarianese/UNESC, iParque, Rod. Gov. Jorge Lacerda, km 4,5, CEP 88806-000, Criciuma, SC, Brazil. FAU - Peterson, M AU - Peterson M AD - Post-Graduate Program in Science and Materials Engineering, Universidade do Extremo Sul Catarianese/UNESC, Av. Universitaria, 1105, CEP 88806-000, Criciuma, Santa Catarina, Brazil; Laboratory of Advanced Materials and Processes, Universidade do Extremo Sul Catarianese/UNESC, iParque, Rod. Gov. Jorge Lacerda, km 4,5, CEP 88806-000, Criciuma, SC, Brazil. FAU - Fiori, M A AU - Fiori MA AD - Post-Graduation Program in Environmental Science, Universidade Comunitaria da Regiao de Chapeco (Unochapeco), Chapeco, SC, Brazil; Post-Graduation Program in Technology and Management of the Innovation, Universidade Comunitaria da Regiao de Chapeco (Unochapeco), Chapeco, SC, Brazil. Electronic address: fiori@unochapeco.edu.br. LA - eng PT - Journal Article DEP - 20140313 PL - Netherlands TA - Mater Sci Eng C Mater Biol Appl JT - Materials science & engineering. C, Materials for biological applications JID - 101484109 RN - 0 (Anti-Infective Agents) RN - 0 (Polymers) RN - 9002-88-4 (Polyethylene) RN - J41CSQ7QDS (Zinc) SB - IM MH - Anti-Infective Agents/*chemistry/pharmacology MH - Blood Cells/drug effects MH - DNA Damage/drug effects MH - Glass/*chemistry MH - Gram-Negative Bacteria/drug effects MH - Gram-Positive Bacteria/drug effects MH - Humans MH - Polyethylene/*chemistry/pharmacology MH - Polymers/*chemistry/pharmacology MH - Toxicity Tests MH - Zinc/*chemistry/pharmacology OTO - NOTNLM OT - Antimicrobial HDPE OT - Antimicrobial LLDPE OT - Antimicrobial additives OT - Antimicrobial polymers EDAT- 2014/05/28 06:00 MHDA- 2015/01/16 06:00 CRDT- 2014/05/28 06:00 PHST- 2013/05/07 00:00 [received] PHST- 2014/02/28 00:00 [revised] PHST- 2014/03/04 00:00 [accepted] PHST- 2014/05/28 06:00 [entrez] PHST- 2014/05/28 06:00 [pubmed] PHST- 2015/01/16 06:00 [medline] AID - S0928-4931(14)00132-5 [pii] AID - 10.1016/j.msec.2014.03.015 [doi] PST - ppublish SO - Mater Sci Eng C Mater Biol Appl. 2014 Jun 1;39:403-10. doi: 10.1016/j.msec.2014.03.015. Epub 2014 Mar 13.