PMID- 2486668
OWN - NLM
STAT- MEDLINE
DCOM- 19910221
LR  - 20120531
IS  - 0914-7470 (Print)
IS  - 0914-7470 (Linking)
VI  - 2
IP  - 4
DP  - 1989 Dec
TI  - [Study of fluorescence in situ hybridization for detection of chromosome 
      aberration].
PG  - 436-8
AB  - The authors applied fluorescence in situ hybridization (FISH) technique for the 
      detection of chromosome aberration in interphase nuclei using the probe specific 
      to alphoid repeats on chromosome 11 and X. Chromosome 11 specific probe showed 
      two major spots in lymphocyte nuclei, while X specific probe showed single spot 
      in male and double spots in female respectively. On the other hand three spots 
      were detected in most of the nuclei from HeLa cells with 11 and X specific 
      probes. We concluded that FISH with the use of chromosome specific probe may 
      become a useful and reliable tool for the detection of chromosome aberration in 
      interphase nuclei.
FAU - Yasutake, T
AU  - Yasutake T
AD  - First Department of Surgery, Nagasaki University School of Medicine, Japan.
FAU - Tagawa, Y
AU  - Tagawa Y
FAU - Miyashita, K
AU  - Miyashita K
FAU - Ishikawa, H
AU  - Ishikawa H
FAU - Hara, S
AU  - Hara S
FAU - Okada, D
AU  - Okada D
FAU - Kuwahara, K
AU  - Kuwahara K
FAU - Kawazoe, N
AU  - Kawazoe N
FAU - Yamaguchi, H
AU  - Yamaguchi H
FAU - Tomita, M
AU  - Tomita M
LA  - jpn
PT  - English Abstract
PT  - Journal Article
PL  - Japan
TA  - Hum Cell
JT  - Human cell
JID - 8912329
RN  - 0 (DNA Probes)
SB  - IM
MH  - Cell Nucleus
MH  - Cells, Cultured
MH  - *Chromosome Aberrations
MH  - Chromosomes, Human, Pair 11
MH  - DNA Probes
MH  - Fluorescence
MH  - HeLa Cells
MH  - Humans
MH  - Interphase
MH  - Lymphocytes
MH  - *Nucleic Acid Hybridization
MH  - X Chromosome
EDAT- 1989/12/01 00:00
MHDA- 1989/12/01 00:01
CRDT- 1989/12/01 00:00
PHST- 1989/12/01 00:00 [pubmed]
PHST- 1989/12/01 00:01 [medline]
PHST- 1989/12/01 00:00 [entrez]
PST - ppublish
SO  - Hum Cell. 1989 Dec;2(4):436-8.