PMID- 24874283
OWN - NLM
STAT- MEDLINE
DCOM- 20150514
LR  - 20220409
IS  - 1502-7708 (Electronic)
IS  - 0036-5521 (Linking)
VI  - 49
IP  - 9
DP  - 2014 Sep
TI  - Use of antacids, alginates and proton pump inhibitors: a survey of the general 
      Danish population using an internet panel.
PG  - 1044-50
LID - 10.3109/00365521.2014.923504 [doi]
AB  - OBJECTIVE: Both over-the-counter medicine, such as antacids or alginates, and 
      proton pump inhibitors (PPI) are used for treating acid-related disorders. We 
      sought to describe what characterizes users of these different medicines, 
      including long-term PPI users within the general population. METHOD: A 
      cross-sectional survey was conducted in an internet panel representative of the 
      Danish adult population in 2012. Data queried included antacid/alginate and PPI 
      use, reason for therapy, co-medication, and presence of upper gastrointestinal 
      symptoms. Long-term PPI use was defined as using PPI >/=1/3 of the last year ( approximately 120 
      days). Risk of long-term PPI use was estimated by logistic regression. RESULTS: A 
      total of 18,223 people received the questionnaire, of which 52% (9390) responded. 
      Antacid/alginate use was reported by 23%; 16% reported use of only 
      antacid/alginate. PPI use was reported by 13.6%; 6.2% were defined as long-term 
      PPI users. Antacid/alginate users were younger, used less co-medication, had most 
      often started on therapy because of reflux symptoms, and had less often ongoing 
      symptoms. Risk of long-term PPI use appeared to be increased in male gender, by 
      renewing PPI prescription by phone/e-mail, using co-medication, and having 
      started on PPI for several reasons. Combination of antacid/alginate and PPI was 
      reported by approximately 50% of those on therapy with weekly or daily symptoms. 
      CONCLUSION: 23% of Danish adults were using antacids or alginates and 14% were 
      using PPI, of which one-half were on long-term therapy. Prescription renewal by 
      phone or e-mail and use of other prescription medication were associated with 
      long-term PPI use, indicating a behavioral pattern, in which unnecessary PPI 
      therapy may be maintained.
FAU - Lodrup, Anders
AU  - Lodrup A
AD  - Department of Medicine, Koge Hospital , Koege , Denmark.
FAU - Reimer, Christina
AU  - Reimer C
FAU - Bytzer, Peter
AU  - Bytzer P
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140530
PL  - England
TA  - Scand J Gastroenterol
JT  - Scandinavian journal of gastroenterology
JID - 0060105
RN  - 0 (Alginates)
RN  - 0 (Antacids)
RN  - 0 (Proton Pump Inhibitors)
SB  - IM
MH  - Age Factors
MH  - Alginates/*therapeutic use
MH  - Antacids/*therapeutic use
MH  - Cross-Sectional Studies
MH  - Denmark
MH  - Drug Prescriptions/statistics & numerical data
MH  - Drug Therapy, Combination/statistics & numerical data
MH  - Female
MH  - Gastroesophageal Reflux/complications/*drug therapy
MH  - Humans
MH  - Internet
MH  - Male
MH  - Middle Aged
MH  - Proton Pump Inhibitors/*therapeutic use
MH  - Sex Factors
MH  - Surveys and Questionnaires
MH  - Time Factors
OTO - NOTNLM
OT  - alginate
OT  - antacid
OT  - dyspepsia
OT  - general population
OT  - internet panel
OT  - over-the-counter medicine
OT  - proton pump inhibitor
OT  - reflux
EDAT- 2014/05/31 06:00
MHDA- 2015/05/15 06:00
CRDT- 2014/05/31 06:00
PHST- 2014/05/31 06:00 [entrez]
PHST- 2014/05/31 06:00 [pubmed]
PHST- 2015/05/15 06:00 [medline]
AID - 10.3109/00365521.2014.923504 [doi]
PST - ppublish
SO  - Scand J Gastroenterol. 2014 Sep;49(9):1044-50. doi: 10.3109/00365521.2014.923504. 
      Epub 2014 May 30.