PMID- 24874447
OWN - NLM
STAT- MEDLINE
DCOM- 20141204
LR  - 20230425
IS  - 1879-0372 (Electronic)
IS  - 0952-7915 (Print)
IS  - 0952-7915 (Linking)
VI  - 29
DP  - 2014 Aug
TI  - Complementary diversification of dendritic cells and innate lymphoid cells.
PG  - 69-78
LID - S0952-7915(14)00071-5 [pii]
LID - 10.1016/j.coi.2014.04.006 [doi]
AB  - Dendritic cells (DCs) are professional antigen presenting cells conventionally 
      thought to mediate cellular adaptive immune responses. Recent studies have led to 
      the recognition of a non-redundant role for DCs in orchestrating innate immune 
      responses, and in particular, for DC subset-specific interactions with innate 
      lymphoid cells (ILCs). Recently recognized as important effectors of early immune 
      responses, ILCs develop into subsets which mirror the transcriptional and 
      cytokine profile of their T cell subset counterparts. DC diversification into 
      functional subsets provides for modules of pathogen sensing and cytokine 
      production that direct pathogen-appropriate ILC and T cell responses. This review 
      focuses on the recent advances in the understanding of DC development, and their 
      function in orchestrating the innate immune modules.
CI  - Copyright (c) 2014 Elsevier Ltd. All rights reserved.
FAU - Briseno, Carlos G
AU  - Briseno CG
AD  - Department of Pathology and Immunology, Washington University in St. Louis, 
      School of Medicine, 660 S. Euclid Avenue, St. Louis, MO 63110, USA.
FAU - Murphy, Theresa L
AU  - Murphy TL
AD  - Department of Pathology and Immunology, Washington University in St. Louis, 
      School of Medicine, 660 S. Euclid Avenue, St. Louis, MO 63110, USA.
FAU - Murphy, Kenneth M
AU  - Murphy KM
AD  - Department of Pathology and Immunology, Washington University in St. Louis, 
      School of Medicine, 660 S. Euclid Avenue, St. Louis, MO 63110, USA; Howard Hughes 
      Medical Institute, Washington University in St. Louis, School of Medicine, 660 S. 
      Euclid Avenue, St. Louis, MO 63110, USA. Electronic address: kmurphy@wustl.edu.
LA  - eng
GR  - HHMI/Howard Hughes Medical Institute/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20140527
PL  - England
TA  - Curr Opin Immunol
JT  - Current opinion in immunology
JID - 8900118
RN  - 0 (Cytokines)
SB  - IM
MH  - Animals
MH  - Bone Marrow/immunology
MH  - Cytokines/immunology
MH  - Dendritic Cells/*immunology
MH  - Homeostasis
MH  - Humans
MH  - *Immunity, Innate
MH  - Lymphocytes/*immunology
PMC - PMC5161034
MID - NIHMS833974
EDAT- 2014/05/31 06:00
MHDA- 2014/12/15 06:00
PMCR- 2016/12/16
CRDT- 2014/05/31 06:00
PHST- 2014/02/18 00:00 [received]
PHST- 2014/03/28 00:00 [revised]
PHST- 2014/04/29 00:00 [accepted]
PHST- 2014/05/31 06:00 [entrez]
PHST- 2014/05/31 06:00 [pubmed]
PHST- 2014/12/15 06:00 [medline]
PHST- 2016/12/16 00:00 [pmc-release]
AID - S0952-7915(14)00071-5 [pii]
AID - 10.1016/j.coi.2014.04.006 [doi]
PST - ppublish
SO  - Curr Opin Immunol. 2014 Aug;29:69-78. doi: 10.1016/j.coi.2014.04.006. Epub 2014 
      May 27.