PMID- 24876206
OWN - NLM
STAT- MEDLINE
DCOM- 20150713
LR  - 20151119
IS  - 1535-5667 (Electronic)
IS  - 0161-5505 (Linking)
VI  - 55
IP  - 8
DP  - 2014 Aug
TI  - Prevalence of adverse events to radiopharmaceuticals from 2007 to 2011.
PG  - 1308-10
LID - 10.2967/jnumed.114.138057 [doi]
AB  - We studied the changing patterns of radiopharmaceutical use and the incidence of 
      adverse events (AEs) to PET radiopharmaceuticals, non-PET radiopharmaceuticals, 
      and adjunctive nonradioactive pharmaceuticals in nuclear medicine from 2007 to 
      2011. METHODS: Fifteen academic institutions submitted quarterly reports of 
      radiopharmaceutical use and AEs covering 2007-2011. RESULTS: 1,024,177 
      radiopharmaceutical administrations were monitored: 207,281 diagnostic PET, 
      803,696 diagnostic non-PET, and 13,200 therapeutic. In addition, 112,830 
      adjunctive nonradioactive pharmaceutical administrations were monitored. The 
      annual use of bone scintigraphy and radiotracer therapies was unchanged. PET 
      radiopharmaceutical use increased from 17% to 26% of diagnostic procedures (P < 
      0.01). The incidence of radiopharmaceutical AEs was 2.1/10(5) administrations, 
      with no hospitalizations or deaths. CONCLUSION: From 2007 to 2011, PET studies 
      increased, and therapeutic radiopharmaceutical use and bone scintigraphy were 
      unchanged. Over 2 decades, the incidence of AEs has remained stable at 
      2.1-2.3/10(5) dosages.
CI  - (c) 2014 by the Society of Nuclear Medicine and Molecular Imaging, Inc.
FAU - Silberstein, Edward B
AU  - Silberstein EB
AD  - Departments of Radiology and Medicine, University of Cincinnati Medical Center, 
      Cincinnati, Ohio edward.silberstein@uchealth.com.
LA  - eng
PT  - Journal Article
DEP - 20140529
PL  - United States
TA  - J Nucl Med
JT  - Journal of nuclear medicine : official publication, Society of Nuclear Medicine
JID - 0217410
RN  - 0 (Radiopharmaceuticals)
SB  - IM
MH  - Academies and Institutes/statistics & numerical data
MH  - Positron-Emission Tomography
MH  - Prevalence
MH  - Radiopharmaceuticals/*adverse effects/therapeutic use
MH  - *Safety
OTO - NOTNLM
OT  - adverse events
OT  - nuclear medicine safety
OT  - radiopharmaceuticals
EDAT- 2014/05/31 06:00
MHDA- 2015/07/15 06:00
CRDT- 2014/05/31 06:00
PHST- 2014/01/25 00:00 [received]
PHST- 2014/04/22 00:00 [accepted]
PHST- 2014/05/31 06:00 [entrez]
PHST- 2014/05/31 06:00 [pubmed]
PHST- 2015/07/15 06:00 [medline]
AID - jnumed.114.138057 [pii]
AID - 10.2967/jnumed.114.138057 [doi]
PST - ppublish
SO  - J Nucl Med. 2014 Aug;55(8):1308-10. doi: 10.2967/jnumed.114.138057. Epub 2014 May 
      29.