PMID- 24878263 OWN - NLM STAT- MEDLINE DCOM- 20150410 LR - 20140620 IS - 1532-2971 (Electronic) IS - 1090-0233 (Linking) VI - 201 IP - 1 DP - 2014 Jul TI - Canine stage 1 periodontal disease: a latent pathology. PG - 118-20 LID - S1090-0233(14)00189-0 [pii] LID - 10.1016/j.tvjl.2014.05.005 [doi] AB - To evaluate the potential health issues associated with periodontal disease (PD) in dogs, 1004 teeth from 25 dogs were examined. The dogs were randomly selected, aged 2-14 years, and had at least 95% of their teeth at the first PD stage. Significant positive correlations between plaque grade (PG) and gum inflammation, gingival regression, periodontal pocket, age and serum alanine aminotransferase (ALT) activity were identified. In contrast, PG was negatively correlated to total platelet count. Altogether, these findings suggest that prevention and therapy at the first PD stages can have an important impact on the general health condition of dogs. CI - Copyright (c) 2014 Elsevier Ltd. All rights reserved. FAU - Whyte, A AU - Whyte A AD - Department of Animal Pathology, Faculty of Veterinary Sciences, Universidad de Zaragoza, Miguel Servet, 177, 50.013 Zaragoza, Spain. FAU - Bonastre, C AU - Bonastre C AD - Department of Animal Pathology, Faculty of Veterinary Sciences, Universidad de Zaragoza, Miguel Servet, 177, 50.013 Zaragoza, Spain. FAU - Monteagudo, L V AU - Monteagudo LV AD - Department of Anatomy, Embryology and Animal Genetics, Faculty of Veterinary Sciences, Universidad de Zaragoza, Miguel Servet, 177, 50.013 Zaragoza, Spain. FAU - Les, F AU - Les F AD - Department of Animal Pathology, Faculty of Veterinary Sciences, Universidad de Zaragoza, Miguel Servet, 177, 50.013 Zaragoza, Spain. FAU - Obon, J AU - Obon J AD - Department of Human Anatomy and Histology, Faculty of Medicine, Universidad de Zaragoza, Domingo Miral, s/n, 50009 Zaragoza, Spain. FAU - Whyte, J AU - Whyte J AD - Department of Human Anatomy and Histology, Faculty of Medicine, Universidad de Zaragoza, Domingo Miral, s/n, 50009 Zaragoza, Spain. FAU - Tejedor, M T AU - Tejedor MT AD - Department of Anatomy, Embryology and Animal Genetics, Faculty of Veterinary Sciences, Universidad de Zaragoza, Miguel Servet, 177, 50.013 Zaragoza, Spain. Electronic address: ttejedor@unizar.es. LA - eng PT - Journal Article DEP - 20140509 PL - England TA - Vet J JT - Veterinary journal (London, England : 1997) JID - 9706281 SB - IM MH - Animals MH - Dental Plaque/etiology/*veterinary MH - Dog Diseases/*etiology/immunology MH - Dogs MH - Female MH - Gingivitis/etiology/immunology/*veterinary MH - Male MH - Periodontal Diseases/etiology/immunology/*veterinary MH - Spain OTO - NOTNLM OT - Blood parameters OT - Dental plaque OT - Dog OT - Gum inflammation OT - Periodontal disease EDAT- 2014/06/01 06:00 MHDA- 2015/04/11 06:00 CRDT- 2014/06/01 06:00 PHST- 2013/07/15 00:00 [received] PHST- 2014/04/29 00:00 [revised] PHST- 2014/05/04 00:00 [accepted] PHST- 2014/06/01 06:00 [entrez] PHST- 2014/06/01 06:00 [pubmed] PHST- 2015/04/11 06:00 [medline] AID - S1090-0233(14)00189-0 [pii] AID - 10.1016/j.tvjl.2014.05.005 [doi] PST - ppublish SO - Vet J. 2014 Jul;201(1):118-20. doi: 10.1016/j.tvjl.2014.05.005. Epub 2014 May 9.