PMID- 24880858
OWN - NLM
STAT- MEDLINE
DCOM- 20150818
LR  - 20141202
IS  - 1878-1780 (Electronic)
IS  - 1262-3636 (Linking)
VI  - 40
IP  - 5
DP  - 2014 Nov
TI  - Prevalence of diabetes and depressive symptomatology and their effect on 
      mortality risk in elderly Italians: The Italian Longitudinal Study on Aging.
PG  - 373-8
LID - S1262-3636(14)00083-4 [pii]
LID - 10.1016/j.diabet.2014.05.001 [doi]
AB  - AIM: This study assessed the prevalence of depressive symptomatology (DS) in 
      older individuals with diabetes to determine whether diabetes and DS are 
      independent predictors of mortality, and if their coexistence is associated with 
      an increased mortality risk. METHODS: Analyses were based on data from the 
      Italian Longitudinal Study on Aging (ILSA), a prospective community-based cohort 
      study in which 5632 individuals aged 65-84years were enrolled. The role of 
      diabetes and DS in all-cause mortality was evaluated using the Cox model, 
      adjusted for possible confounders, for four groups: 1) those with neither 
      diabetes nor DS (reference group); 2) those with DS but without diabetes; 3) 
      those with diabetes but no DS; and 4) those with both diabetes and DS. RESULTS: 
      Type 2 diabetes mellitus (T2DM) was present in 13.8% of the participants; they 
      presented with higher baseline rates of DS compared with the non-diabetic 
      controls. During the first follow-up period, participants with DS but not 
      diabetes had a 42% higher risk of all-cause mortality compared with the reference 
      control group (HR=1.42; 95% CI: 1.02-1.96), while participants with diabetes but 
      not DS had an 83% higher risk of death than the reference group (HR=1.83; 95% CI: 
      1.19-2.80). The risk of death for those with both disorders was more than twice 
      that for the reference group (HR=2.58; 95% CI: 1.55-4.29). Analyses of deaths 
      from baseline to the second follow-up substantially confirmed these results. 
      CONCLUSION: The prevalence rate of DS is higher in elderly people with diabetes 
      and their coexistence is associated with an increased mortality risk.
CI  - Copyright (c) 2014 Elsevier Masson SAS. All rights reserved.
FAU - Limongi, F
AU  - Limongi F
AD  - National Research Council (CNR), Neuroscience Institute Aging Branch, Via 
      Giustiniani 2, 35128 Padua, Italy. Electronic address: 
      federica.limongi@in.cnr.it.
FAU - Noale, M
AU  - Noale M
AD  - National Research Council (CNR), Neuroscience Institute Aging Branch, Via 
      Giustiniani 2, 35128 Padua, Italy.
FAU - Crepaldi, G
AU  - Crepaldi G
AD  - National Research Council (CNR), Neuroscience Institute Aging Branch, Via 
      Giustiniani 2, 35128 Padua, Italy.
FAU - Maggi, S
AU  - Maggi S
AD  - National Research Council (CNR), Neuroscience Institute Aging Branch, Via 
      Giustiniani 2, 35128 Padua, Italy.
CN  - ILSA Working Group
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140528
PL  - France
TA  - Diabetes Metab
JT  - Diabetes & metabolism
JID - 9607599
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Aging/*psychology
MH  - Comorbidity
MH  - Depression/*epidemiology/etiology/mortality
MH  - Diabetes Mellitus, Type 2/*epidemiology/mortality/psychology
MH  - Female
MH  - Follow-Up Studies
MH  - Geriatric Assessment
MH  - Humans
MH  - Italy/epidemiology
MH  - Longitudinal Studies
MH  - Male
MH  - Mortality/trends
MH  - Odds Ratio
MH  - Predictive Value of Tests
MH  - Prevalence
MH  - Proportional Hazards Models
MH  - Risk Assessment
MH  - Risk Factors
OTO - NOTNLM
OT  - Depressive symptomatology
OT  - Diabetes mellitus
OT  - Elderly
OT  - Mortality risk
OT  - Prevalence
FIR - Scafato, E
IR  - Scafato E
FIR - Farchi, G
IR  - Farchi G
FIR - Galluzzo, L
IR  - Galluzzo L
FIR - Gandin, C
IR  - Gandin C
FIR - Capurso, A
IR  - Capurso A
FIR - Panza, F
IR  - Panza F
FIR - Solfrizzi, V
IR  - Solfrizzi V
FIR - Lepore, V
IR  - Lepore V
FIR - Livrea, P
IR  - Livrea P
FIR - Motta, L
IR  - Motta L
FIR - Carnazzo, G
IR  - Carnazzo G
FIR - Motta, M
IR  - Motta M
FIR - Bentivegna, P
IR  - Bentivegna P
FIR - Bonaiuto, S
IR  - Bonaiuto S
FIR - Cruciani, G
IR  - Cruciani G
FIR - Postacchini, D
IR  - Postacchini D
FIR - Inzitari, D
IR  - Inzitari D
FIR - Amaducci, L
IR  - Amaducci L
FIR - Di Carlo, A
IR  - Di Carlo A
FIR - Baldereschi, M
IR  - Baldereschi M
FIR - Gandolfo, C
IR  - Gandolfo C
FIR - Conti, M
IR  - Conti M
FIR - Canal, N
IR  - Canal N
FIR - Franceschi, M
IR  - Franceschi M
FIR - Scarlato, G
IR  - Scarlato G
FIR - Candelise, L
IR  - Candelise L
FIR - Scapini, E
IR  - Scapini E
FIR - Rengo, F
IR  - Rengo F
FIR - Abete, P
IR  - Abete P
FIR - Cacciatore, F
IR  - Cacciatore F
FIR - Enzi, G
IR  - Enzi G
FIR - Battistin, L
IR  - Battistin L
FIR - Sergi, G
IR  - Sergi G
FIR - Crepaldi, G
IR  - Crepaldi G
FIR - Maggi, S
IR  - Maggi S
FIR - Minicuci, N
IR  - Minicuci N
FIR - Noale, M
IR  - Noale M
FIR - Grigoletto, F
IR  - Grigoletto F
FIR - Perissinotto, E
IR  - Perissinotto E
FIR - Carbonin, P
IR  - Carbonin P
EDAT- 2014/06/02 06:00
MHDA- 2015/08/19 06:00
CRDT- 2014/06/02 06:00
PHST- 2014/01/23 00:00 [received]
PHST- 2014/04/29 00:00 [revised]
PHST- 2014/05/02 00:00 [accepted]
PHST- 2014/06/02 06:00 [entrez]
PHST- 2014/06/02 06:00 [pubmed]
PHST- 2015/08/19 06:00 [medline]
AID - S1262-3636(14)00083-4 [pii]
AID - 10.1016/j.diabet.2014.05.001 [doi]
PST - ppublish
SO  - Diabetes Metab. 2014 Nov;40(5):373-8. doi: 10.1016/j.diabet.2014.05.001. Epub 
      2014 May 28.