PMID- 24882518
OWN - NLM
STAT- MEDLINE
DCOM- 20150515
LR  - 20190907
IS  - 1348-4540 (Electronic)
IS  - 0918-8959 (Linking)
VI  - 61
IP  - 8
DP  - 2014
TI  - Sarcomatoid carcinoma of the kidney in a MEN1 patient: case report and genetic 
      profile.
PG  - 781-7
AB  - Renal tumors are exceedingly rare in Multiple Endocrine Neoplasia type 1 (MEN1), 
      a pleyotropic hereditary cancer disorder affecting the endocrine system. Herein 
      we report a unique case of renal sarcomatoid carcinoma with concomitant 
      ipsilateral non-secreting adrenal adenoma occurring in a young male MEN1 patient, 
      previously operated for hyperparathyroidism and multiple pancreatic 
      neuroendocrine neoplasms. Molecular analysis in the MEN1 locus at 11q13 showed 
      loss of heterozygosity in the adrenal lesion, while kidney cancer was unrelated 
      to MEN1 syndrome.
FAU - Cavalli, Tiziana
AU  - Cavalli T
AD  - Department of Surgery and Translational Medicine, University of Florence, 
      Florence, Italy.
FAU - Giudici, Francesco
AU  - Giudici F
FAU - Nesi, Gabriella
AU  - Nesi G
FAU - Marini, Francesca
AU  - Marini F
FAU - Giusti, Francesca
AU  - Giusti F
FAU - Cavalli, Loredana
AU  - Cavalli L
FAU - Brandi, Maria Luisa
AU  - Brandi ML
FAU - Tonelli, Francesco
AU  - Tonelli F
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20140530
PL  - Japan
TA  - Endocr J
JT  - Endocrine journal
JID - 9313485
RN  - 0 (MEN1 protein, human)
RN  - 0 (Proto-Oncogene Proteins)
SB  - IM
MH  - Adenoma/complications/diagnosis/genetics
MH  - Adrenal Gland Neoplasms/complications/diagnosis/genetics
MH  - Adult
MH  - Carcinoma, Renal Cell/complications/*diagnosis/genetics
MH  - DNA Mutational Analysis
MH  - Humans
MH  - Kidney Neoplasms/complications/*diagnosis/genetics
MH  - Male
MH  - Multiple Endocrine Neoplasia Type 1/complications/*diagnosis/genetics
MH  - Neoplasms, Multiple Primary/diagnosis/genetics
MH  - Proto-Oncogene Proteins/*genetics
EDAT- 2014/06/03 06:00
MHDA- 2015/05/16 06:00
CRDT- 2014/06/03 06:00
PHST- 2014/06/03 06:00 [entrez]
PHST- 2014/06/03 06:00 [pubmed]
PHST- 2015/05/16 06:00 [medline]
AID - DN/JST.JSTAGE/endocrj/EJ14-0021 [pii]
AID - 10.1507/endocrj.ej14-0021 [doi]
PST - ppublish
SO  - Endocr J. 2014;61(8):781-7. doi: 10.1507/endocrj.ej14-0021. Epub 2014 May 30.