PMID- 24885694
OWN - NLM
STAT- MEDLINE
DCOM- 20150623
LR  - 20211021
IS  - 1471-2458 (Electronic)
IS  - 1471-2458 (Linking)
VI  - 14
DP  - 2014 May 14
TI  - Conversation about Serostatus decreases risk of acquiring HIV: results from a 
      case control study comparing MSM with recent HIV infection and HIV negative 
      controls.
PG  - 453
LID - 10.1186/1471-2458-14-453 [doi]
AB  - BACKGROUND: Data on knowledge, attitudes, behaviour and practices (KABP) of 
      persons with recent HIV infection compared to controls with negative HIV test 
      result provide information on current risk patterns and can help to re-focus HIV 
      prevention strategies. METHODS: From March 2008 through May 2010, persons newly 
      diagnosed with HIV (cases) and HIV-negative controls were recruited by physicians 
      in Germany. To distinguish recent (< 5 months) from longstanding (> 5 months) 
      infection, dried blood spots from people newly diagnosed with HIV were tested 
      with the BED IgG-capture ELISA. Cases and controls completed a 
      KABP-questionnaire. We compared cases with recent infection and controls among 
      men having sex with men (MSM) regarding reported risk behaviour in the previous 6 
      months. To detect differences, unadjusted Odds Ratios (OR) were calculated and 
      multivariate analysis was performed. RESULTS: Cases and controls did not differ 
      in terms of knowledge on transmission risks, HIV testing frequency, partnership 
      status, or regarding the frequency of any unprotected sex with partners known to 
      be HIV-positive or assumed to be HIV-negative. Cases more often reported a 
      shorter duration of partnership (< 6 months) with a primary partner than controls 
      (OR = 3.9; p = 0.003) and indicated lower rates of condom use outside of primary 
      relationships, with acquaintances (OR = 2.5; p = 0.01), and with persons met 
      online (OR = 4.5; p = 0.04). Unprotected sex with persons of unknown 
      HIV-serostatus was more often indicated by cases than controls (OR = 3.0; 
      p = 0.003). Having a conversation about HIV serostatus before having sex was 
      associated with a lower risk of infection (OR = 0.2; p = 0.01). In multivariate 
      analysis "being always safe" (always using a condom when having sex in different 
      situations outside of a relationship) and talking about serostatus before sex 
      (OR = 0.23; p = 0.004; OR = 0.14; p = 0.014) were negatively associated with HIV- 
      infection. CONCLUSIONS: There were no significant differences regarding knowledge 
      about HIV-transmission risks among cases and controls. Differences in risk 
      behaviour were observed regarding unprotected sex with partners of unknown 
      HIV-serostatus and duration of primary partnership at the time of diagnosis, 
      suggesting some HIV-transmissions occurring in newly formed partnerships. The 
      practice of discussing serostatus with prospective sex partners before engaging 
      in sex seems to be protective for HIV-transmission.
FAU - Santos-Hovener, Claudia
AU  - Santos-Hovener C
AD  - Department for Infectious Disease Epidemiology, HIV/AIDS, STI and Blood-borne 
      Infections Unit, Robert Koch Institute, Berlin, Germany. Santos-HoevenerC@rki.de.
FAU - Zimmermann, Ruth
AU  - Zimmermann R
FAU - Kucherer, Claudia
AU  - Kucherer C
FAU - Batzing-Feigenbaum, Jorg
AU  - Batzing-Feigenbaum J
FAU - Wildner, Stephan
AU  - Wildner S
FAU - Hamouda, Osamah
AU  - Hamouda O
FAU - Marcus, Ulrich
AU  - Marcus U
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140514
PL  - England
TA  - BMC Public Health
JT  - BMC public health
JID - 100968562
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Case-Control Studies
MH  - *Communication
MH  - Germany
MH  - HIV Infections/blood/diagnosis/*prevention & control
MH  - *HIV Seronegativity
MH  - *Health Knowledge, Attitudes, Practice
MH  - *Homosexuality, Male
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Prospective Studies
MH  - *Risk-Taking
MH  - Surveys and Questionnaires
PMC - PMC4046506
EDAT- 2014/06/03 06:00
MHDA- 2015/06/24 06:00
PMCR- 2014/05/14
CRDT- 2014/06/03 06:00
PHST- 2013/12/17 00:00 [received]
PHST- 2014/05/06 00:00 [accepted]
PHST- 2014/06/03 06:00 [entrez]
PHST- 2014/06/03 06:00 [pubmed]
PHST- 2015/06/24 06:00 [medline]
PHST- 2014/05/14 00:00 [pmc-release]
AID - 1471-2458-14-453 [pii]
AID - 10.1186/1471-2458-14-453 [doi]
PST - epublish
SO  - BMC Public Health. 2014 May 14;14:453. doi: 10.1186/1471-2458-14-453.