PMID- 24893671
OWN - NLM
STAT- MEDLINE
DCOM- 20151029
LR  - 20150128
IS  - 1753-0407 (Electronic)
IS  - 1753-0407 (Linking)
VI  - 7
IP  - 2
DP  - 2015 Mar
TI  - Meta-analysis of prospective studies on the effects of nut consumption on 
      hypertension and type 2 diabetes mellitus.
PG  - 202-12
LID - 10.1111/1753-0407.12173 [doi]
AB  - BACKGROUND: Inconclusive reports have been published on the consumption of nuts 
      and the risk of hypertension and type 2 diabetes mellitus (T2DM). We performed a 
      meta-analysis of prospective studies to assess the effects of nut consumption on 
      hypertension and T2DM risks. METHODS: A PUBMED and EMBASE database search was 
      performed. Summary relative risks (SRRs) and 95% confidence intervals (CIs) were 
      calculated using a random-effects model. Q and I2 statistics were used to examine 
      between-study heterogeneity. RESULTS: A total of eight articles with nine 
      prospective cohort studies (three hypertension studies and six T2DM studies) were 
      selected. Using random effects models, we found that compared with never/rare 
      consumers of nuts, those consuming >2 servings per week had an 8% lower risk of 
      hypertension (SRR = 0.92, 95% CI: 0.87-0.97, P(heterogeneity)  = 0.590, I2 
       = 0%), while consumption of nuts at one serving per week had similar risk 
      (SRR = 0.97, 95% CI: 0.83-1.13). In addition, nuts consumption was not associated 
      with risk of T2DM (SRRs = 0.98, 95% CI: 0.84-1.15; P(heterogeneity)  = 0.008, I2 
       = 67.7%) on the basis of the highest versus lowest analysis. This null 
      association was also shown in the dose-response analysis. CONCLUSION: Findings 
      from this meta-analysis indicate that consumption of nuts (>2 servings/week) may 
      be inversely associated with hypertension risk, but not with T2DM risk.
CI  - (c) 2014 Ruijin Hospital, Shanghai Jiaotong University School of Medicine and Wiley 
      Publishing Asia Pty Ltd.
FAU - Guo, Kai
AU  - Guo K
AD  - Department of Cardiology, Xinhua Hospital, Shanghai Jiao Tong University, School 
      of Medicine, Shanghai, China.
FAU - Zhou, Zhiwen
AU  - Zhou Z
FAU - Jiang, Yibo
AU  - Jiang Y
FAU - Li, Wei
AU  - Li W
FAU - Li, Yigang
AU  - Li Y
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
DEP - 20140729
PL  - Australia
TA  - J Diabetes
JT  - Journal of diabetes
JID - 101504326
SB  - IM
MH  - Databases, Factual
MH  - Diabetes Mellitus, Type 2/*epidemiology
MH  - Humans
MH  - Hypertension/*epidemiology/*prevention & control
MH  - Incidence
MH  - *Nuts
MH  - Prognosis
MH  - Prospective Studies
MH  - Risk Reduction Behavior
OTO - NOTNLM
OT  - hypertension
OT  - meta-analysis
OT  - nut consumption
OT  - type 2 diabetes mellitus
OT  - 关键词：高血压，meta分析，食用坚果，2型糖尿病
EDAT- 2014/06/05 06:00
MHDA- 2015/10/30 06:00
CRDT- 2014/06/05 06:00
PHST- 2013/12/04 00:00 [received]
PHST- 2014/04/20 00:00 [revised]
PHST- 2014/05/15 00:00 [accepted]
PHST- 2014/06/05 06:00 [entrez]
PHST- 2014/06/05 06:00 [pubmed]
PHST- 2015/10/30 06:00 [medline]
AID - 10.1111/1753-0407.12173 [doi]
PST - ppublish
SO  - J Diabetes. 2015 Mar;7(2):202-12. doi: 10.1111/1753-0407.12173. Epub 2014 Jul 29.