PMID- 24900107 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20140606 LR - 20211021 IS - 1869-3474 (Print) IS - 1869-3482 (Electronic) IS - 1869-3474 (Linking) VI - 47 IP - 3 DP - 2013 Sep TI - Myocardial Fibrosis in Hypertrophic Cardiomyopathy Demonstrated by Integrated Cardiac F-18 FDG PET/MR. PG - 196-200 LID - 10.1007/s13139-013-0201-0 [doi] AB - Hypertrophic cardiomyopathy (HCM) is a common condition defined as a diffuse or segmental left ventricular (LV) hypertrophy with a nondilated and hyperdynamic chamber as well as cardiac arrhythmias. Cardiac MR (CMR) imaging is a key modality for evaluation of HCM. In addition to the assessment of LV wall thickness, LV function and aortic flow, CMR is capable of estimation of late gadolinium enhancement (LGE) in affected myocardium which has been shown to have a direct correlation with incidence and severity of arrhythmias in HCM. In patients with HCM, LGE on CMR is presumed to represent intramyocardial fibrosis. Meanwhile, F-18 FDG myocardial PET has been sporadically studied in HCM, mostly for evaluation of the metabolic status of a hypertrophic myocardial segment, especially after interventions or to demonstrate partial myocardial fibrosis. We presented here the case of a 25-year-old male patient referred for simultaneous F-18 FDG cardiac PET/MR for the evaluation of septal hypertrophy. The PET/MR revealed myocardial fibrosis in the septum associated with FDG-defect and LGE. FAU - Kong, Eun-Jung AU - Kong EJ AD - Department of Nuclear Medicine, Yeungnam University, College of Medicine, Daegu Hyunchungro 170, South Korea. FAU - Lee, Sang-Hee AU - Lee SH AD - Department of Internal Medicine, Yeungnam University, College of Medicine, Daegu Hyunchungro 170, South Korea. FAU - Cho, Ihn-Ho AU - Cho IH AD - Department of Nuclear Medicine, Yeungnam University, College of Medicine, Daegu Hyunchungro 170, South Korea. LA - eng PT - Journal Article DEP - 20130410 PL - Germany TA - Nucl Med Mol Imaging JT - Nuclear medicine and molecular imaging JID - 101530478 PMC - PMC4035195 OTO - NOTNLM OT - Cardiovascular magnetic resonance OT - FDG OT - Fibrosis OT - Hypertrophic cardiomyopathy OT - PET/MRI EDAT- 2014/06/06 06:00 MHDA- 2014/06/06 06:01 PMCR- 2014/09/01 CRDT- 2014/06/06 06:00 PHST- 2013/01/13 00:00 [received] PHST- 2013/02/19 00:00 [revised] PHST- 2013/03/13 00:00 [accepted] PHST- 2014/06/06 06:00 [entrez] PHST- 2014/06/06 06:00 [pubmed] PHST- 2014/06/06 06:01 [medline] PHST- 2014/09/01 00:00 [pmc-release] AID - 201 [pii] AID - 10.1007/s13139-013-0201-0 [doi] PST - ppublish SO - Nucl Med Mol Imaging. 2013 Sep;47(3):196-200. doi: 10.1007/s13139-013-0201-0. Epub 2013 Apr 10.