PMID- 24904074
OWN - NLM
STAT- MEDLINE
DCOM- 20160510
LR  - 20220309
IS  - 1460-2199 (Electronic)
IS  - 1047-3211 (Linking)
VI  - 25
IP  - 9
DP  - 2015 Sep
TI  - Local and Global Correlations between Neurons in the Middle Temporal Area of 
      Primate Visual Cortex.
PG  - 3182-96
LID - 10.1093/cercor/bhu111 [doi]
AB  - In humans and other primates, the analysis of visual motion includes populations 
      of neurons in the middle-temporal (MT) area of visual cortex. Motion analysis 
      will be constrained by the structure of neural correlations in these populations. 
      Here, we use multi-electrode arrays to measure correlations in anesthetized 
      marmoset, a New World monkey where area MT lies exposed on the cortical surface. 
      We measured correlations in the spike count between pairs of neurons and within 
      populations of neurons, for moving dot fields and moving gratings. Correlations 
      were weaker in area MT than in area V1. The magnitude of correlations in area MT 
      diminished with distance between receptive fields, and difference in preferred 
      direction. Correlations during presentation of moving gratings were stronger than 
      those during presentation of moving dot fields, extended further across cortex, 
      and were less dependent on the functional properties of neurons. Analysis of the 
      timescales of correlation suggests presence of 2 mechanisms. A local mechanism, 
      associated with near-synchronous spiking activity, is strongest in nearby neurons 
      with similar direction preference and is independent of visual stimulus. A global 
      mechanism, operating over larger spatial scales and longer timescales, is 
      independent of direction preference and is modulated by the type of visual 
      stimulus presented.
CI  - (c) The Author 2014. Published by Oxford University Press. All rights reserved. For 
      Permissions, please e-mail: journals.permissions@oup.com.
FAU - Solomon, Selina S
AU  - Solomon SS
AD  - ARC Centre of Excellence in Vision Science, Sydney, NSW, Australia Discipline of 
      Physiology, School of Medical Sciences and Bosch Institute, The University of 
      Sydney, Sydney, NSW 2006, Australia.
FAU - Chen, Spencer C
AU  - Chen SC
AD  - ARC Centre of Excellence in Vision Science, Sydney, NSW, Australia Discipline of 
      Physiology, School of Medical Sciences and Bosch Institute, The University of 
      Sydney, Sydney, NSW 2006, Australia.
FAU - Morley, John W
AU  - Morley JW
AD  - School of Medicine, University of Western Sydney, Campbelltown, NSW 2560, 
      Australia.
FAU - Solomon, Samuel G
AU  - Solomon SG
AD  - ARC Centre of Excellence in Vision Science, Sydney, NSW, Australia Discipline of 
      Physiology, School of Medical Sciences and Bosch Institute, The University of 
      Sydney, Sydney, NSW 2006, Australia Department of Experimental Psychology, 
      University College London, WC1P 0AH, UK.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140605
PL  - United States
TA  - Cereb Cortex
JT  - Cerebral cortex (New York, N.Y. : 1991)
JID - 9110718
SB  - IM
MH  - Action Potentials/*physiology
MH  - Animals
MH  - Callithrix
MH  - Female
MH  - Male
MH  - Motion Perception/physiology
MH  - Nerve Net/*physiology
MH  - Neurons/*physiology
MH  - Orientation
MH  - Photic Stimulation
MH  - *Statistics as Topic
MH  - Time Factors
MH  - Visual Cortex/*cytology
MH  - Visual Fields/physiology
MH  - Visual Pathways/physiology
MH  - Visual Perception
OTO - NOTNLM
OT  - area MT
OT  - extrastriate
OT  - marmoset
OT  - population coding
OT  - visual motion
EDAT- 2014/06/07 06:00
MHDA- 2016/05/11 06:00
CRDT- 2014/06/07 06:00
PHST- 2014/06/07 06:00 [entrez]
PHST- 2014/06/07 06:00 [pubmed]
PHST- 2016/05/11 06:00 [medline]
AID - bhu111 [pii]
AID - 10.1093/cercor/bhu111 [doi]
PST - ppublish
SO  - Cereb Cortex. 2015 Sep;25(9):3182-96. doi: 10.1093/cercor/bhu111. Epub 2014 Jun 
      5.