PMID- 24906342
OWN - NLM
STAT- MEDLINE
DCOM- 20150415
LR  - 20211021
IS  - 1435-702X (Electronic)
IS  - 0721-832X (Linking)
VI  - 252
IP  - 11
DP  - 2014 Nov
TI  - Evaluation of congenital excavated optic disc anomalies with spectral-domain and 
      swept-source optical coherence tomography.
PG  - 1853-60
LID - 10.1007/s00417-014-2680-9 [doi]
AB  - PURPOSE: To investigate the anatomic characteristics of congenital excavated 
      optic disc anomalies by using fundus photography, spectral-domain optical 
      coherence tomography (SD-OCT), and swept-source optical coherence tomography 
      (SS-OCT). METHODS: Fourteen eyes from 13 patients with congenital excavated optic 
      disc anomalies underwent a complete ophthalmologic examination that included 
      best-corrected visual acuity evaluation, fundus photography, and SD-OCT. SS-OCT 
      was performed in cases of peripapillary staphyloma cases in which the excavation 
      depth could not be detected with SD-OCT. On the basis of the funduscopic and OCT 
      findings, patients were classified as morning glory syndrome, optic disc 
      coloboma, or peripapillary staphyloma. RESULTS: Seven eyes with morning glory 
      syndrome were characterized by the presence of the preretinal tractional membrane 
      in front of the excavated optic disc and could be divided into two groups: three 
      eyes without retinal excavation, and four eyes with retinal excavation. Four eyes 
      with optic disc coloboma showed inferiorly decentered scleral excavations with 
      shallow optic disc excavation detectable by SD-OCT. Three eyes with peripapillary 
      staphyloma showed deep excavation, the depth of which could not be detected by 
      SD-OCT. SS-OCT and enhanced depth imaging SD-OCT images focused on the bottom 
      revealed membranous structure at the bottom of the excavation in two cases with 
      peripapillary staphyloma. CONCLUSIONS: SD-OCT and SS-OCT are helpful for 
      differential diagnosis of excavated optic disc anomalies. Morning glory syndrome, 
      optic disc coloboma, and peripapillary staphyloma were respectively characterized 
      by the presence of a preretinal tractional membrane, inferiorly decentered 
      excavation, and an excavation deeper than that observed in morning glory syndrome 
      and optic disc coloboma.
FAU - Lee, Kyoung Min
AU  - Lee KM
AD  - Department of Ophthalmology, Seoul National University College of Medicine, 
      Seoul, South Korea.
FAU - Woo, Se Joon
AU  - Woo SJ
FAU - Hwang, Jeong-Min
AU  - Hwang JM
LA  - eng
PT  - Journal Article
DEP - 20140607
PL  - Germany
TA  - Graefes Arch Clin Exp Ophthalmol
JT  - Graefe's archive for clinical and experimental ophthalmology = Albrecht von 
      Graefes Archiv fur klinische und experimentelle Ophthalmologie
JID - 8205248
RN  - Coloboma of optic nerve
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Child
MH  - Child, Preschool
MH  - Coloboma/*diagnosis
MH  - Diagnosis, Differential
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Optic Disk/abnormalities/*pathology
MH  - Optic Nerve/*abnormalities
MH  - Photography
MH  - *Tomography, Optical Coherence/methods
MH  - Visual Acuity/physiology
MH  - Young Adult
EDAT- 2014/06/08 06:00
MHDA- 2015/04/16 06:00
CRDT- 2014/06/08 06:00
PHST- 2014/01/28 00:00 [received]
PHST- 2014/05/20 00:00 [accepted]
PHST- 2014/05/13 00:00 [revised]
PHST- 2014/06/08 06:00 [entrez]
PHST- 2014/06/08 06:00 [pubmed]
PHST- 2015/04/16 06:00 [medline]
AID - 10.1007/s00417-014-2680-9 [doi]
PST - ppublish
SO  - Graefes Arch Clin Exp Ophthalmol. 2014 Nov;252(11):1853-60. doi: 
      10.1007/s00417-014-2680-9. Epub 2014 Jun 7.