PMID- 24907758 OWN - NLM STAT- MEDLINE DCOM- 20150127 LR - 20161125 IS - 1873-0191 (Electronic) IS - 0928-4931 (Linking) VI - 41 DP - 2014 Aug 1 TI - Synthesis of poly acrylic acid modified silver nanoparticles and their antimicrobial activities. PG - 249-54 LID - S0928-4931(14)00251-3 [pii] LID - 10.1016/j.msec.2014.04.059 [doi] AB - Poly acrylic acid modified silver (Ag/PAA) nanoparticles (NPs) have been successfully synthesized in the aqueous solution by using tannic acid as a reductant. The structure, morphology and composition of Ag/PAA NPs were characterized by various techniques such as X-ray powder diffraction (XRD), transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), ultraviolet-visible absorption spectroscopy (UV-vis) and thermogravimetry analysis (TGA). The results show that PAA/Ag NPs have a quasi-ball shape with an average diameter of 10 nm and exhibit well crystalline, and the reaction conditions have some effect on products morphology and size distribution. In addition, the as-synthesized Ag/PAA NPs antimicrobial activities against Escherichia coli (E. coli), Pseudomonas aeruginosa (P. aeruginosa) and Staphylococcus aureus (S. aureus) were evaluated by the methods of broth dilution, cup diffusion, optical density (OD600) and electron microscopy observation. The as-synthesized Ag/PAA NPs exhibit excellent antibacterial activity. The antimicrobial mechanism may be attributed to the damaging of bacterial cell membrane and causing leakage of cytoplasm. CI - Copyright (c) 2014 Elsevier B.V. All rights reserved. FAU - Ni, Zhihui AU - Ni Z AD - Key Laboratory for Special Functional Materials of Ministry of Education, Henan University, Kaifeng 475004, PR China. FAU - Wang, Zhihua AU - Wang Z AD - Institute of Environmental and Analytical Sciences, College of Chemistry and Chemical Engineering, Henan University, Kaifeng 475004, PR China. FAU - Sun, Lei AU - Sun L AD - Key Laboratory for Special Functional Materials of Ministry of Education, Henan University, Kaifeng 475004, PR China. Electronic address: sunlei@henu.edu.cn. FAU - Li, Binjie AU - Li B AD - Key Laboratory of Cellular and Molecular Immunology, Henan University, Kaifeng 475004, PR China. FAU - Zhao, Yanbao AU - Zhao Y AD - Key Laboratory for Special Functional Materials of Ministry of Education, Henan University, Kaifeng 475004, PR China. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20140502 PL - Netherlands TA - Mater Sci Eng C Mater Biol Appl JT - Materials science & engineering. C, Materials for biological applications JID - 101484109 RN - 0 (Acrylic Resins) RN - 0 (Anti-Infective Agents) RN - 0 (Tannins) RN - 3M4G523W1G (Silver) RN - 4Q93RCW27E (carbopol 940) SB - IM MH - Acrylic Resins/*chemistry MH - Anti-Infective Agents/*chemical synthesis/pharmacology MH - Escherichia coli/drug effects MH - Metal Nanoparticles/*chemistry/toxicity MH - Microbial Sensitivity Tests MH - Oxidation-Reduction MH - Particle Size MH - Pseudomonas aeruginosa/drug effects MH - Silver/*chemistry MH - Staphylococcus aureus/drug effects MH - Tannins/chemistry OTO - NOTNLM OT - Antimicrobial property OT - Poly acrylic acid OT - Silver nanoparticles OT - Synthesis EDAT- 2014/06/09 06:00 MHDA- 2015/01/28 06:00 CRDT- 2014/06/09 06:00 PHST- 2014/01/07 00:00 [received] PHST- 2014/03/17 00:00 [revised] PHST- 2014/04/22 00:00 [accepted] PHST- 2014/06/09 06:00 [entrez] PHST- 2014/06/09 06:00 [pubmed] PHST- 2015/01/28 06:00 [medline] AID - S0928-4931(14)00251-3 [pii] AID - 10.1016/j.msec.2014.04.059 [doi] PST - ppublish SO - Mater Sci Eng C Mater Biol Appl. 2014 Aug 1;41:249-54. doi: 10.1016/j.msec.2014.04.059. Epub 2014 May 2.