PMID- 24910109
OWN - NLM
STAT- MEDLINE
DCOM- 20150922
LR  - 20141230
IS  - 1753-0407 (Electronic)
IS  - 1753-0407 (Linking)
VI  - 7
IP  - 1
DP  - 2015 Jan
TI  - Prevalence and associated factors of obstructive sleep apnea in hospitalized 
      patients with type 2 diabetes in Beijing, China 2.
PG  - 16-23
LID - 10.1111/1753-0407.12180 [doi]
AB  - BACKGROUND: The aim of the present study was to assess the prevalence and risk 
      factors associated with obstructive sleep apnea (OSA) in hospitalized patients 
      with type 2 diabetes mellitus (T2DM) in China. METHODS: Patients with T2DM who 
      were hospitalized in four facilities in Beijing were invited to participate in 
      the study. In all, 337 patients were enrolled consecutively, and 210 (62.3%) 
      completed the study. Data from 472 patients in a non-consecutive expanding study 
      were analyzed for the association study. A portable monitoring device was used to 
      detect the presence of OSA. The apnea-hypopnea index (AHI) and the lowest level 
      of oxygen saturation during the night were recorded to evaluate the severity of 
      OSA. Logistic regression analysis was used to estimate the odds ratio (OR) for 
      OSA for risk factors. RESULTS: The prevalence of OSA was 66.7%. The prevalence of 
      moderate to severe OSA (AHI >/=15/h) was 20.0%. The multi-adjusted OR (95% 
      confidence interval) estimating OSA corresponding to a 1-year increase in age was 
      1.06 (1.04, 1.08), whereas that to a 1-kg/m(2) increase in body mass index (BMI) 
      was 1.18 (1.11, 1.26). The lowest oxygen saturation was associated with 
      proliferative diabetic retinopathy (PDR) and cerebral infarction; the 
      multivariate adjusted OR (95% CI) corresponding to a 1% increase in lowest oxygen 
      saturation were 0.95 (0.92, 0.99) and 0.97 (0.94, 0.99), respectively. 
      CONCLUSION: A high prevalence of OSA was observed in this sample of patients with 
      T2DM in China. Age and BMI were associated with the presence of OSA. The lowest 
      oxygen saturation was independently associated with the presence of PDR and 
      cerebral infarction.
CI  - (c) 2014 Ruijin Hospital, Shanghai Jiaotong University School of Medicine and Wiley 
      Publishing Asia Pty Ltd.
FAU - Zhang, Rui
AU  - Zhang R
AD  - Department of Endocrinology and Metabolism, Peking University People's Hospital, 
      Beijing, China.
FAU - Guo, Xiaohui
AU  - Guo X
FAU - Guo, Lixin
AU  - Guo L
FAU - Lu, Juming
AU  - Lu J
FAU - Zhou, Xianghai
AU  - Zhou X
FAU - Ji, Linong
AU  - Ji L
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140906
PL  - Australia
TA  - J Diabetes
JT  - Journal of diabetes
JID - 101504326
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Body Mass Index
MH  - China/epidemiology
MH  - Diabetes Complications/*epidemiology/etiology
MH  - Diabetes Mellitus, Type 2/complications/*physiopathology
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Prevalence
MH  - Risk Factors
MH  - Sleep Apnea, Obstructive/*epidemiology/etiology
MH  - Young Adult
OTO - NOTNLM
OT  - cerebral infarction
OT  - obstructive sleep apnea
OT  - proliferative diabetic retinopathy
OT  - type 2 diabetes
OT  - 关键词：脑梗死，阻塞性睡眠呼吸暂停，增殖期糖尿病视网膜病变，2型糖尿病
EDAT- 2014/06/10 06:00
MHDA- 2015/09/24 06:00
CRDT- 2014/06/10 06:00
PHST- 2014/04/14 00:00 [received]
PHST- 2014/07/11 00:00 [revised]
PHST- 2014/05/24 00:00 [accepted]
PHST- 2014/06/10 06:00 [entrez]
PHST- 2014/06/10 06:00 [pubmed]
PHST- 2015/09/24 06:00 [medline]
AID - 10.1111/1753-0407.12180 [doi]
PST - ppublish
SO  - J Diabetes. 2015 Jan;7(1):16-23. doi: 10.1111/1753-0407.12180. Epub 2014 Sep 6.