PMID- 24917315
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20140612
LR  - 20140611
IS  - 1365-1501 (Print)
IS  - 1365-1501 (Linking)
VI  - 14
IP  - 3
DP  - 2010 Sep
TI  - Remission, prediction and stability of symptoms in schizophrenia: A naturalistic 
      12-month follow-up study.
PG  - 160-7
LID - 10.3109/13651500903531365 [doi]
AB  - Abstract Objective. Since its introduction in 2005, schizophrenia remission 
      consensus criteria have been used in several prospective and cross-sectional 
      studies. The aim of this prospective assessment of patients with schizophrenia 
      was to employ the remission criteria in a naturalistic study design. Methods. One 
      hundred and six patients with schizophrenia (ICD10 F 20.x) were enrolled into the 
      study during inpatient treatment. Remission criteria with respect to changes in 
      psychopathology ratings were obtained by trained interviewers at discharge and at 
      12-month follow-up using BPRS. Furthermore, information on social functioning and 
      treatment-related quality of life were assessed using GAF (Global Assessment of 
      Functioning) and SWN-K (Subjective Wellbeing under Neuroleptic Treatment Scale). 
      Results. A total of 13.2% of the patients were found to meet remission criteria 
      during follow-up. While there was no significant change in the mean BPRS scores, 
      14.2% of the subjects showed significant worsening and 29.2% significant 
      improvement of their psychotic symptoms. Subsequent logistic regression analysis, 
      explaining approximately 32% of symptomatic remission variance, indicated a 
      significant influence of BPRS-Overall-Score and independent living at discharge. 
      Conclusions. The results of this naturalistic study indicate that only a minority 
      of former inpatients with schizophrenia achieve remission after 1 year and 
      relevant subgroups of patients have significant bi-directional changes in 
      symptoms during follow-up.
FAU - Wolter, Arne
AU  - Wolter A
AD  - Psychiatrieverbund Oldenburger Land gGmbH, Karl-Jaspers-Klinik, Bad Zwischenahn, 
      Germany.
FAU - Wolfgang Preuss, Ulrich
AU  - Wolfgang Preuss U
FAU - Richard Krischke, Norbert
AU  - Richard Krischke N
FAU - Mooi Wong, Wei
AU  - Mooi Wong W
FAU - Zimmermann, JoRg
AU  - Zimmermann J
LA  - eng
PT  - Journal Article
PL  - England
TA  - Int J Psychiatry Clin Pract
JT  - International journal of psychiatry in clinical practice
JID - 9709509
OTO - NOTNLM
OT  - Schizophrenia
OT  - follow-up
OT  - prediction
OT  - quality management
OT  - remission
EDAT- 2010/09/01 00:00
MHDA- 2010/09/01 00:01
CRDT- 2014/06/12 06:00
PHST- 2014/06/12 06:00 [entrez]
PHST- 2010/09/01 00:00 [pubmed]
PHST- 2010/09/01 00:01 [medline]
AID - 10.3109/13651500903531365 [doi]
PST - ppublish
SO  - Int J Psychiatry Clin Pract. 2010 Sep;14(3):160-7. doi: 
      10.3109/13651500903531365.