PMID- 24920379
OWN - NLM
STAT- MEDLINE
DCOM- 20150120
LR  - 20140612
IS  - 1440-1819 (Electronic)
IS  - 1323-1316 (Linking)
VI  - 68
IP  - 6
DP  - 2014 Jun
TI  - Neural responses to various rewards and feedback in the brains of adolescent 
      Internet addicts detected by functional magnetic resonance imaging.
PG  - 463-70
LID - 10.1111/pcn.12154 [doi]
AB  - AIM: This study aimed to examine differences in brain activation for various 
      types of reward and feedback in adolescent Internet addicts (AIA) and normal 
      adolescents (NA) using functional magnetic resonance imaging (fMRI). METHODS: AIA 
      (n = 15) and NA (n = 15) underwent fMRI while performing easy tasks for which 
      performance feedback (PF), social reward (SR) (such as compliments), or monetary 
      reward (MR) was given. Using the no reward (NR) condition, three types of 
      contrasts (PF-NR, SR-NR, and MR-NR) were analyzed. RESULTS: In NA, we observed 
      activation in the reward-related subcortical system, self-related brain region, 
      and other brain areas for the three contrasts, but these brain areas showed 
      almost no activation in AIA. Instead, AIA showed significant activation in the 
      dorsolateral prefrontal cortex for the PF-NR contrast and the negative 
      correlation was found between the level of activation in the left superior 
      temporal gyrus (BA 22) and the duration of Internet game use per day in AIA. 
      CONCLUSION: These findings suggest that AIA show reduced levels of self-related 
      brain activation and decreased reward sensitivity irrespective of the type of 
      reward and feedback. AIA may be only sensitive to error monitoring regardless of 
      positive feelings, such as sense of satisfaction or achievement.
CI  - (c) 2014 The Authors. Psychiatry and Clinical Neurosciences (c) 2014 Japanese Society 
      of Psychiatry and Neurology.
FAU - Kim, Ji-Eun
AU  - Kim JE
AD  - Department of Psychiatry, Chungbuk National University Hospital, Cheongju, Korea.
FAU - Son, Jung-Woo
AU  - Son JW
FAU - Choi, Won-Hee
AU  - Choi WH
FAU - Kim, Yeoung-Rang
AU  - Kim YR
FAU - Oh, Jong-Hyun
AU  - Oh JH
FAU - Lee, Seungbok
AU  - Lee S
FAU - Kim, Jang-Kyu
AU  - Kim JK
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140219
PL  - Australia
TA  - Psychiatry Clin Neurosci
JT  - Psychiatry and clinical neurosciences
JID - 9513551
SB  - IM
MH  - Adolescent
MH  - Behavior, Addictive/*physiopathology/psychology
MH  - Brain/*physiopathology
MH  - Brain Mapping
MH  - *Feedback, Psychological
MH  - Female
MH  - Humans
MH  - *Internet
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Republic of Korea
MH  - *Reward
MH  - Video Games/psychology
MH  - Wechsler Scales
OTO - NOTNLM
OT  - adolescent Internet addiction
OT  - feedback
OT  - functional magnetic resonance imaging
OT  - reward
EDAT- 2014/06/13 06:00
MHDA- 2015/01/21 06:00
CRDT- 2014/06/13 06:00
PHST- 2013/05/22 00:00 [received]
PHST- 2013/12/07 00:00 [revised]
PHST- 2013/12/19 00:00 [accepted]
PHST- 2014/06/13 06:00 [entrez]
PHST- 2014/06/13 06:00 [pubmed]
PHST- 2015/01/21 06:00 [medline]
AID - 10.1111/pcn.12154 [doi]
PST - ppublish
SO  - Psychiatry Clin Neurosci. 2014 Jun;68(6):463-70. doi: 10.1111/pcn.12154. Epub 
      2014 Feb 19.