PMID- 24923120 OWN - NLM STAT- MEDLINE DCOM- 20140723 LR - 20161018 IS - 0023-2130 (Print) IS - 0023-2130 (Linking) IP - 2 DP - 2014 Feb TI - [Dynamics of inflammatory mediators and indices of antiendotoxic immunity in children with purulent-destructive pneumonia]. PG - 36-8 AB - There were examined 220 children, in whom purulent-destructive pneumonia (PDP) was diagnosed. Level of anti-inflammatory mediators and indices of the antiendotoxine immunity was determined in the blood serum, using immunoassay analysis, after admittance to hospital. There was established, that in PDP in children the concentration of anti-inflammatory mediators interleucines (IL--1 beta, IL-6) is enhanced, as well as of the tumor necrosis factor-- alpha (TNF-alpha), C-reactive protein (CRP), while titre of antibodies to endotoxine class G lowers, and the level of lipopolisaccharid-binded protein (LBP) and soluble form of CD14 receptor (sCD14) is raised, not depending from the patient state severity. FAU - Pritulo, L F AU - Pritulo LF FAU - Bisiuk, Iu A AU - Bisiuk IuA LA - rus PT - English Abstract PT - Journal Article PL - Ukraine TA - Klin Khir JT - Klinichna khirurhiia JID - 9516872 RN - 0 (Cytokines) RN - 0 (IL1B protein, human) RN - 0 (IL6 protein, human) RN - 0 (Interleukin-1beta) RN - 0 (Interleukin-6) RN - 0 (Tumor Necrosis Factor-alpha) RN - 9007-41-4 (C-Reactive Protein) SB - IM MH - Adolescent MH - C-Reactive Protein/*analysis MH - Case-Control Studies MH - Child MH - Child, Preschool MH - Cytokines/*blood MH - Data Interpretation, Statistical MH - Humans MH - *Immunity, Humoral MH - Infant MH - Interleukin-1beta/blood MH - Interleukin-6/blood MH - Kinetics MH - Necrosis MH - Pneumonia, Bacterial/blood/*immunology/*pathology MH - Severity of Illness Index MH - Suppuration MH - Tumor Necrosis Factor-alpha/blood EDAT- 2014/06/14 06:00 MHDA- 2014/07/24 06:00 CRDT- 2014/06/14 06:00 PHST- 2014/06/14 06:00 [entrez] PHST- 2014/06/14 06:00 [pubmed] PHST- 2014/07/24 06:00 [medline] PST - ppublish SO - Klin Khir. 2014 Feb;(2):36-8.