PMID- 24923430
OWN - NLM
STAT- MEDLINE
DCOM- 20150629
LR  - 20151119
IS  - 1747-4949 (Electronic)
IS  - 1747-4930 (Linking)
VI  - 9
IP  - 8
DP  - 2014 Dec
TI  - Impact of living and socioeconomic characteristics on cardiovascular risk in 
      ischemic stroke patients.
PG  - 1065-72
LID - 10.1111/ijs.12290 [doi]
AB  - OBJECTIVE: We aimed to stratify the risk of vascular event recurrence in patients 
      with cerebral infarction according to living and socioeconomic characteristics 
      and geographic region. METHOD: The Outcomes in Patients with TIA and 
      Cerebrovascular Disease (OPTIC) study is an international prospective study of 
      patients aged 45 years or older who required secondary prevention of stroke 
      [following either an acute transient ischemic attack, minor ischemic strokes, or 
      recent (less than six-months previous), stable, first-ever, nondisabling ischemic 
      stroke]. A total 3635 patients from 245 centers in 17 countries in four regions 
      (Latin America, Middle East, North Africa, South Africa) were enrolled between 
      2007 and 2008. The outcome measure was the two-year rate of a composite of major 
      vascular events (vascular death, myocardial infarction and stroke). RESULTS: 
      During the two-year follow-up period, 516 patients experienced at least one major 
      cardiovascular event, resulting in an event rate of 15.6% (95% confidence 
      interval 14.4-16.9%). Event rates varied across geographical region (P < 0.001), 
      ranging from 13.0% in Latin America to 20.7% in North Africa. Unemployment 
      status, living in a rural area, not living in fully serviced accommodation (i.e., 
      house or apartment with its own electricity, toilet and water supply), no health 
      insurance coverage, and low educational level (less than two-years of schooling) 
      were predictors of major vascular events. Major vascular event rates steeply 
      increased with the number of low-quality living/socioeconomic conditions (from 
      13.4% to 47.9%, adjusted P value for trend <0.001). CONCLUSION: Vascular risk in 
      stroke patients in low- and middle-income countries varies not only with the 
      number of arterial beds involved but also with socioeconomic variables.
CI  - (c) 2014 World Stroke Organization.
FAU - Amarenco, Pierre
AU  - Amarenco P
AD  - Department of Neurology and Stroke Center, Bichat University Hospital, Paris, 
      France; INSERM U-698 and Paris-Diderot University, Paris, France.
FAU - Abboud, Halim
AU  - Abboud H
FAU - Labreuche, Julien
AU  - Labreuche J
FAU - Arauz, Antonio
AU  - Arauz A
FAU - Bryer, Alan
AU  - Bryer A
FAU - Lavados, Pablo M
AU  - Lavados PM
FAU - Massaro, Ayrton
AU  - Massaro A
FAU - Munoz Collazos, Mario
AU  - Munoz Collazos M
FAU - Steg, Philippe Gabriel
AU  - Steg PG
FAU - Yamout, Bassem I
AU  - Yamout BI
FAU - Vicaut, Eric
AU  - Vicaut E
CN  - OPTIC Registry Investigators
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
PT  - Research Support, Non-U.S. Gov't
DEP - 20140612
PL  - United States
TA  - Int J Stroke
JT  - International journal of stroke : official journal of the International Stroke 
      Society
JID - 101274068
SB  - IM
MH  - *Activities of Daily Living
MH  - Africa
MH  - Aged
MH  - Aged, 80 and over
MH  - Brain Ischemia/complications
MH  - Cardiovascular Diseases/*epidemiology
MH  - Female
MH  - Humans
MH  - International Cooperation
MH  - Latin America
MH  - Longitudinal Studies
MH  - Male
MH  - Middle Aged
MH  - Middle East
MH  - Multivariate Analysis
MH  - Retrospective Studies
MH  - Risk Factors
MH  - *Social Class
MH  - Stroke/*epidemiology/etiology/*psychology
MH  - Surveys and Questionnaires
MH  - Time Factors
OTO - NOTNLM
OT  - atherothrombotic
OT  - countries
OT  - epidemiology
OT  - ischemic stroke
OT  - risk factors
OT  - socioeconomic factors
EDAT- 2014/06/14 06:00
MHDA- 2015/06/30 06:00
CRDT- 2014/06/14 06:00
PHST- 2013/10/29 00:00 [received]
PHST- 2014/03/16 00:00 [accepted]
PHST- 2014/06/14 06:00 [entrez]
PHST- 2014/06/14 06:00 [pubmed]
PHST- 2015/06/30 06:00 [medline]
AID - 10.1111/ijs.12290 [doi]
PST - ppublish
SO  - Int J Stroke. 2014 Dec;9(8):1065-72. doi: 10.1111/ijs.12290. Epub 2014 Jun 12.