PMID- 24925803
OWN - NLM
STAT- MEDLINE
DCOM- 20140731
LR  - 20140613
IS  - 1879-1913 (Electronic)
IS  - 0002-9149 (Linking)
VI  - 114
IP  - 1
DP  - 2014 Jul 1
TI  - Transradial percutaneous coronary interventions in acute coronary syndrome.
PG  - 160-8
LID - S0002-9149(14)00974-6 [pii]
LID - 10.1016/j.amjcard.2014.04.017 [doi]
AB  - Transradial access (TRA) is becoming increasingly used worldwide for percutaneous 
      coronary intervention (PCI) after acute coronary syndromes (ACS). TRA compared 
      with transfemoral access has been noted to improve clinical outcomes in clinical 
      trials and large registry cohort studies. However, much of the benefits of TRA 
      PCI are noted in patients with ST elevation myocardial infarction (STEMI) 
      undergoing primary PCI, where TRA PCI has been associated with reductions in 
      major bleeding events and potentially lower short- and long-term mortality rates. 
      Although much less data exist for TRA PCI in unstable angina and/or non-ST 
      elevation myocardial infarction, similar reductions in bleeding and mortality 
      have not been consistently described. Differences in outcome benefit with TRA PCI 
      among various ACS subtypes may be attributable to the potentially increased 
      inherent risk of periprocedural bleeding in STEMI compared with unstable angina 
      and/or non-ST elevation myocardial infarction. Pre- and intra-procedural factors 
      associated with STEMI treatment, such as use of pharmacoinvasive therapy and 
      aggressive antithrombotic regimens likely increase bleeding risk in patients. In 
      conclusion, this review describes the evidence for TRA PCI across the spectrum of 
      ACS and highlights why differences in clinical benefit may exist among ACS 
      subtypes.
CI  - Copyright (c) 2014 Elsevier Inc. All rights reserved.
FAU - Khan, Razi
AU  - Khan R
AD  - Department of Medicine, Montreal Heart Institute and Universite de Montreal, 
      Montreal, Quebec, Canada.
FAU - Ly, Hung Q
AU  - Ly HQ
AD  - Department of Medicine, Montreal Heart Institute and Universite de Montreal, 
      Montreal, Quebec, Canada. Electronic address: qh.ly@umontreal.ca.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20140418
PL  - United States
TA  - Am J Cardiol
JT  - The American journal of cardiology
JID - 0207277
SB  - IM
MH  - Acute Coronary Syndrome/*therapy
MH  - Hemorrhage/*prevention & control
MH  - Humans
MH  - Percutaneous Coronary Intervention/*methods
MH  - Radial Artery/*surgery
EDAT- 2014/06/14 06:00
MHDA- 2014/08/01 06:00
CRDT- 2014/06/14 06:00
PHST- 2014/01/27 00:00 [received]
PHST- 2014/04/03 00:00 [revised]
PHST- 2014/04/03 00:00 [accepted]
PHST- 2014/06/14 06:00 [entrez]
PHST- 2014/06/14 06:00 [pubmed]
PHST- 2014/08/01 06:00 [medline]
AID - S0002-9149(14)00974-6 [pii]
AID - 10.1016/j.amjcard.2014.04.017 [doi]
PST - ppublish
SO  - Am J Cardiol. 2014 Jul 1;114(1):160-8. doi: 10.1016/j.amjcard.2014.04.017. Epub 
      2014 Apr 18.