PMID- 24936758
OWN - NLM
STAT- MEDLINE
DCOM- 20160906
LR  - 20140618
IS  - 2651-3463 (Electronic)
IS  - 1300-2163 (Linking)
VI  - 25
IP  - 2
DP  - 2014 Summer
TI  - [The impact of disease course and type of episodes in bipolar disorder on 
      caregiver burden].
PG  - 114-23
AB  - OBJECTIVE: The aim of this study was to determine how the disease course and type 
      of episodes in patients with bipolar I disorder (BPD-I) affect caregiver burden. 
      MATERIALS AND METHODS: The study was conducted between February and July 2010, 
      and included 89 euthymic-state BPD-I patients (55 with a natural course and 34 
      with >/=1 mixed episode or a rapid cycling course) diagnosed according to DSM-IV-TR 
      criteria and 89 of their caregivers. The patients were evaluated using a 
      sociodemographic clinical form, the Hamilton Depression Rating Scale (HAM-D), 
      Young Mania Rating Scale (YMRS), and Global Assessment of Functionality Scale 
      (GAFS). The caregivers were evaluated using a sociodemographic form and the Zarit 
      Caregiver Burden Interview (ZCBI). RESULTS: In all, 44% of the BPD-I patients' 
      caregivers had moderate to severe burden. More of the caregivers of patients with 
      rapid cycling or mixed episodes had social relationships negatively affected by 
      caregiver burden (P < 0.01). The mean YMRS score was higher in the caregivers 
      with moderate to severe burden (P< 0.01). As patient age, YMRS score, number of 
      manic episodes, duration of illness, and duration of caregiving during the 
      euthymic period increased (P < 0.05) the level of caregiver-perceived dependency 
      also increased; as caregiver age and the duration of caregiving increased, the 
      perception of economic burden decreased (P< 0.05). CONCLUSION: BPD-I patient 
      caregiving, even when patients are in a euthymic state, results in considerable 
      caregiver burden. Mixed episodes or rapid cycling increases the severity of 
      caregiver burden, as does the number of manic episodes and the presence of 
      subsyndromal manic features.
FAU - Erten, Evrim
AU  - Erten E
FAU - Alpman, Nilay
AU  - Alpman N
FAU - Ozdemir, Armagan
AU  - Ozdemir A
FAU - Fistikci, Nurhan
AU  - Fistikci N
LA  - tur
PT  - English Abstract
PT  - Journal Article
TT  - Bipolar I bozuklugu olan hastalarda donem ve seyirozelliklerinin bakici yukune 
      etkisi.
PL  - Turkey
TA  - Turk Psikiyatri Derg
JT  - Turk psikiyatri dergisi = Turkish journal of psychiatry
JID - 9425936
SB  - IM
MH  - Bipolar Disorder/pathology/*therapy
MH  - *Caregivers
MH  - *Cost of Illness
MH  - Humans
MH  - Psychiatric Status Rating Scales
MH  - *Quality of Life
MH  - Severity of Illness Index
EDAT- 2014/06/18 06:00
MHDA- 2016/09/07 06:00
CRDT- 2014/06/18 06:00
PHST- 2014/06/18 06:00 [entrez]
PHST- 2014/06/18 06:00 [pubmed]
PHST- 2016/09/07 06:00 [medline]
AID - 936 [pii]
PST - ppublish
SO  - Turk Psikiyatri Derg. 2014 Summer;25(2):114-23.